Adipose Tissue Quality After Different Liposuction Methods in the Same Person
Official title: A Prospective Within-Subject Comparison of Adipose Tissue Viability and Cellular Characteristics Following Ultrasound- and Power-Assisted Liposuction and Aspiration Modalities
Run by Apyx Medical · NCT07820397 · Data updated 2026-11-12
This study tests whether fat harvested with different liposuction technologies stays healthier when collected from the same person.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years to 65 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Apyx Medical Industry-sponsored |
| Locations | 2 sites (Concord, Ohio and 1 other locations) |
| Status | Recruiting |
| Started | August 6, 2026 |
| Main results expected | December 31, 2026 |
| Study ends | April 30, 2027 |
| Registry record updated | September 15, 2026 |
| Trial ID | NCT07820397 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 30–65 planning elective liposuction involving two or more areas and able to provide informed consent.
✕Probably not a fit
Participants should not expect direct clinical benefits beyond their standard liposuction procedure.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Participants will undergo liposuction using different technologies on matched body areas, with paired fat samples collected from contralateral or anatomically matched sites. Each person serves as their own control to compare viable adipocytes, stromal vascular fraction, metabolic activity, and fat composition across methods. The study is focused on tissue quality and does not promise direct clinical benefits beyond the planned procedure. No treatment change is being tested for patient care outside the research aims.
Why it matters
Potential benefit: If successful, findings could help identify liposuction methods that preserve fat tissue quality for future research or clinical applications.
How similar studies have gone: Prior work in fat tissue handling suggests technology and method can influence adipose tissue characteristics, but direct intra-individual comparisons of multiple devices are less common.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female aged 30 to 65 years, inclusive. * Planned elective liposuction/body contouring procedure involving two or more anatomical areas (e.g., arms, abdomen, flanks, thighs, and/or back) with sufficient distribution to permit collection of paired adipose tissue samples from contralateral or anatomically matched treatment areas. * Investigator determines the subject is an appropriate candidate for the planned procedure and study participation. * Adequate adipose tissue is present to permit collection of required paired fat samples without impacting the planned surgical outcome. * Able to understand and sign the informed consent form. * Willing and able to comply with study requirements. * If applicable, female subjects of childbearing potential must have a negative urine pregnancy test on the day of procedure. Exclusion Criteria: * Prior liposuction or surgical intervention in the planned treatment areas that, in the opinion of the investigator, may affect adipose tissue characteristics or study assessments. * Prior treatment of the planned treatment areas with energy-based devices (e.g., ultrasound, radiofrequency, laser) that, in the opinion of the investigator, may affect adipose tissue characteristics or study assessments. * Significant skin laxity, fibrosis, scarring, or other abnormal tissue characteristics in the planned treatment areas that could impact fat harvest quality or comparability between sites. * Current smoker or use of nicotine-containing products within 4 weeks prior to the procedure. * Known metabolic or systemic conditions that may affect adipose tissue biology or wound healing, including but not limited to: * uncontrolled diabetes mellitus * significant vascular disease * connective tissue disorders * Use of medications known to significantly affect fat metabolism, tissue healing, or inflammatory response, including: * chronic systemic corticosteroids * immunosuppressive therapies * GLP-1 receptor agonists (e.g., semaglutide, tirzepatide) within 4 weeks prior to the procedure * Active local or systemic infection at the time of the procedure. * Known coagulopathy or use of anticoagulant therapy that cannot be safely discontinued prior to surgery. * Pregnant or breastfeeding subjects. * Body mass index (BMI) outside the range of 20-35 kg/m², inclusive. * Inadequate adipose tissue volume or distribution to permit paired sample collection from contralateral or anatomically matched areas. * Participation in another interventional clinical study that, in the opinion of the investigator, could interfere with study endpoints. * Any condition that, in the opinion of the investigator, would make the subject unsuitable for participation or could confound study results.
Where it's running
-
Mentor Plastic Surgery
Concord, Ohio, United States Recruiting -
Pearl Plastic Surgery
Olympia, Washington, United States Recruiting
Study contacts
- Principal investigator: Paul Vanek, MD — Mentor Plastic Surgery
- Study coordinator: Global Senior Director, Clinical Affairs
- Email: research@apyxmedical.com
- Phone: 1-800-537-2790
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.