ADHD&me: See if self-esteem improves in youth with ADHD
Official title: ADHD&me: a Randomized Controlled Trial to Target Self-esteem in Youth With ADHD
Run by Universiteit Leiden · NCT07504107 · Data updated 2026-11-12
This trial tests whether the ADHD&me CBT program can raise self-esteem in people aged 16–25 with ADHD, compared to a waitlist control.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 16 Years to 25 Years |
| Sex | All |
| Enrollment | 110 (estimated) |
| Sponsor | Universiteit Leiden Academic / other |
| Locations | 1 site (Haarlem) |
| Status | Recruiting |
| Started | March 25, 2026 |
| Main results expected | March 31, 2028 |
| Study ends | March 31, 2028 |
| Registry record updated | May 14, 2026 |
| Trial ID | NCT07504107 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Youth aged 16–25 with a confirmed ADHD diagnosis and low self-esteem as determined by structured screening.
✕Probably not a fit
Individuals without low self-esteem or those not responsive to CBT-based approaches may not benefit to the same extent.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized trial investigates whether the ADHD&me CBT-based intervention can improve self-esteem and related outcomes in young people with ADHD. Participants are aged 16–25 and are randomized to immediate treatment or a waitlist control, with the control group receiving the intervention after eight weeks. The program consists of seven individual therapy sessions and aims to reduce masking of ADHD behaviors and associated anxiety, depression, and stress. The study uses a structured inclusion process to identify low self-esteem and confirms ADHD diagnosis through standardized assessments. Primary questions focus on self-esteem changes and maintenance over time, while secondary outcomes include mental health symptoms and functional aspects related to ADHD.
Why it matters
Potential benefit: If successful, participants may experience higher self-esteem and better management of ADHD-related symptoms in daily life.
How similar studies have gone: Previous CBT-based efforts for ADHD-related self-perception have shown potential, but this specific ADHD&me approach and its randomized design are novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria:
* 16-25 years old.
* Official ADHD diagnosis, that is confirmed by research team using the clinical interview MINI-S.
* Low self-esteem, determined through a structured and multi-step procedure to minimize subjectivity:
* Referral by clinician. Clinicians from participating institutions identify potential participants. To ensure a uniform understanding of the study population and inclusion criteria, all clinicians receive specific training. The researcher(s) conduction the baseline assessment are also familiar with these training materials, so that the inclusion procedure is applied consistently.
* Telephone screening. Two items from the Rosenberg Self-Esteem Scale (RSES; Rosenberg, 1965) are administered ("At times I think I am no good at all" and "All in all, I am inclined to think I am a failure"). A score of 3 (agree) or 4 (strongly agree) on either of these items is considered indicative of low self-esteem.
* Baseline confirmation. During the baseline measurement, the full Rosenberg Self-Esteem Scale is administered. A cutoff score of \< 15 is used as an objective reference point. This score is combined with a standardized clinical interview conducted by a trained researcher psychologist. At the ADHD section of the MINI-S at the baseline measurement, participants are asked by the researcher psychologist how their symptoms interfere with domains such as work, study, relationships, and self-esteem. If self-esteem is not mentioned, a follow-up question will be asked: "Many people with ADHD feel their symptoms affect their self-esteem, for example due to repeated negative feed- back, feeling like they are not good at things, or failing short. Do you recognize this in yourself"? Based on the participant's response, the trained researcher psychologist interviewer forms a professional, clinical impression of whether there are indicators of persistently low self-esteem (i.e.,insecurity, fear of failure, strong reactions to criticism, perfectionism, distress related to ADHD symptoms). This clinical assessment approach is based on examples provided by the Diagnostic Interview for ADHD in Adults (DIVA-2-NL; Kooij \& Francken, 2010). In all doubtful cases, the inclusion decision will be discussed in consensus meetings with the research team and supervisor, ensuring high inter-rater reliability.
* Pharmacological treatment for ADHD is allowed, but medication dose should be stabilized for a minimum of 4 weeks at baseline measurement (T0). Although changes in ADHD medication during the study are not preferred, they may occur in practice. Any such changed will be carefully documented.
Exclusion Criteria:
* Concurrent psychopathology that requires immediate attention (e.g., severe depression, suicidal thoughts/risk of suicide (as determined by the referring therapist and/or research team). Other comorbidity is allowed.
* Undergoing any concurrent psychological treatment during the study, including any form of therapy for ADHD (e.g., CBT for planning skills). Psychoeducation completed prior to the study entry is allowed, but not during the study.
* Low self-esteem that directly stems from a traumatic experience, which would indicate the need for trauma-specific treatment. This will be determined by the referring therapist. If someone in addition suffers from low self-esteem due to the ADHD symptoms, an appropriate timing of each treatment will be dis- cussed by the referring therapist and potential client.
* IQ \< 80 assessed with two WAIS-IV subscales (Wechsler, 2008): Vocabulary and Block Design.
* Severe substance use (as determined by the referring therapist and/or research team).
* Confirmed Autism Spectrum Disorder (ASD) diagnosis. This also applies when the referring therapist indicates that an ASD diagnosis is very likely, even if it has not yet been established. Since ASD diagnostic procedures are time-consuming and fall outside the scope of this research project, formal ASD assessment will not be conducted within this study.
Note. If included participants receive unforeseen supportive sessions outside the research setting, or if unforeseen medication changes occur during the study, these will be documented and considered during the analysis.
Where it's running
-
Psychologenpraktijk Kuin
Haarlem, Netherlands Recruiting
Study contacts
- Study coordinator: Bianca Boyer
- Email: b.e.boyer@fsw.leidenuniv.nl
- Phone: +31 71 5272727
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.