Addressing psychological distress related to Ebola in Central Uganda

Proposal to Address the Medium- to Long-term EBOLA Associated Psychological Distress and Psychosocial Problems in Mubende District in Central Uganda (Ebola+D Project)

Not applicable Interventional MRC/UVRI and LSHTM Uganda Research Unit · NCT06093646

This study is testing a new program to help people in Central Uganda who are feeling mentally distressed because of Ebola by providing them with support and care over a year.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1000 (estimated)
Ages18 Years and up
SexAll
SponsorMRC/UVRI and LSHTM Uganda Research Unit Academic / other
Locations1 site (Kampala)
Trial IDNCT06093646 on ClinicalTrials.gov

What this trial studies

This project aims to screen individuals attending healthcare facilities in Mubende District for psychological distress associated with Ebola Virus Disease using the WHO Self Report Questionnaire. Those identified with significant distress will receive the Ebola+D intervention, a collaborative model designed to address their mental health and psychosocial needs. Participants will be followed for 12 months with assessments at baseline, 3 months, and 12 months to evaluate the effectiveness of the intervention.

Who should consider this trial

Good fit: Ideal candidates include community members aged 18 and above from Mubende District who exhibit significant psychological distress as indicated by the WHO SRQ-20.

Not a fit: Patients who are unable to engage with the research process due to sensory or cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the mental health and psychosocial well-being of individuals affected by Ebola in the region.

How similar studies have performed: While there have been various interventions addressing mental health in post-epidemic contexts, this specific approach targeting Ebola-related psychological distress is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Community member of Mubende district staying within the catchment area of the primary health care facility (PHCF);
* 18years and above,
* Able to communicate in either English or Luganda (local language spoken in the study region and the language into which the questionnaires will be translated),
* Has a WHO SRQ-20 score of 6 and above (except for Ebola survivors who are eligible even when their SRQ-20 score is either below or above 6). -

Exclusion Criteria:

* Unable to engage with the research process for any reason that may include sensory impairment or cognitive impairment

Where this trial is running

Kampala

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ebola Virus DiseaseEbola associated psychological distress
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.