Adding pain neuroscience education to physiotherapy for adults with acute low back pain.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with acute low back pain (pain <6 weeks) will receive conventional physiotherapy and either traditional patient education or pain neuroscience education (PNE) to compare effects on pain and functional disability. The intervention integrates PNE concepts about how the nervous system and thoughts influence pain with routine physical rehabilitation techniques. Outcomes will focus on changes in pain intensity, fear of movement, and daily function over the treatment course. The program is delivered in person at the rehabilitation facility of Iran University of Medical Sciences and excludes patients with red-flag conditions or major comorbidities.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged 18 years and older.
* A primary complaint of acute low back pain (defined as pain between the bottom of the ribs and the gluteal fold), with or without leg pain.
* Pain duration of less than 6 weeks.
* Absence of any "red flags" for serious spinal pathology (e.g., tumor, infection, fracture, cauda equina syndrome), as confirmed by an orthopedist or neurologist.

Exclusion Criteria:

* Low back pain lasting more than 3 months (chronic low back pain).
* History of spinal surgery within the past 3 years.
* Inability to read or understand Persian.
* Diagnosed cognitive impairments.
* Unwillingness to continue the treatment or study protocol.
* Diagnosed rheumatic, neurological, cardiac, metabolic, or respiratory diseases.
* Diagnosis of fibromyalgia, chronic fatigue syndrome, loss of skin sensation, or skin inflammation/swelling in the low back area.
* Presence or emergence of any "red flag" condition.
* Missing more than 3 consecutive treatment sessions.
* Previous participation in Pain Neuroscience Education sessions.

Where it's running

• rehabilitation facility, Iran university of medical science
  Tehran, Iran Recruiting

Study contacts

• Study coordinator: Mohammadreza Pourahmadi
• Email: pourahmadipt@gmail.com
• Phone: 00989122245593

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.