Adding an IPACK block to improve pain management after knee surgery

The Effect of Adding an IPACK Block to the Adductor Canal Block on Postoperative Pain and Hospital Stay in Patients Undergoing Total Knee Arthroplasty Surgery

Observational Aydin Adnan Menderes University · NCT06586840

This study is testing if adding an IPACK block to a standard pain management technique can help people recover better and feel less pain after knee surgery.

Quick facts

Study typeObservational
Enrollment80 (estimated)
Ages18 Years to 85 Years
SexAll
SponsorAydin Adnan Menderes University Academic / other
Locations1 site (Aydin)
Trial IDNCT06586840 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of combining an IPACK block with an Adductor Canal Block for managing postoperative pain in patients undergoing total knee arthroplasty. The goal is to enhance pain relief while preserving motor function, thereby facilitating quicker recovery and mobilization. By utilizing regional anesthesia techniques, the study aims to reduce opioid consumption and associated side effects, ultimately improving patient outcomes and satisfaction. The observational approach will assess the impact of this multimodal analgesia strategy on recovery metrics.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old undergoing elective total knee arthroplasty with ASA physical status I-III.

Not a fit: Patients with severe comorbidities, those undergoing revision surgeries, or those receiving general anesthesia may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve postoperative pain management and recovery times for knee surgery patients.

How similar studies have performed: Previous studies have shown promising results with similar regional anesthesia techniques, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients with written informed consent
2. Patients over 18 years old undergoing elective total knee arthroplasty surgery
3. Patients with ASA I-II-III
4. Patients receiving spinal anesthesia

Exclusion Criteria:

1. Revision knee arthroplasty and bilateral total knee arthroplasty
2. Liver or kidney failure
3. Patients under 18 years old
4. Patients receiving general anesthesia
5. Allergy or intolerance to study medications
6. Body mass index (BMI) \> 40 kg/m²
7. Chronic use of gabapentin/pregabalin (regular use for more than 3 months)
8. Chronic opioid use (opioid use for more than 3 months or daily oral morphine equivalent \> 5 mg/day for 1 month)
9. Patients with ASA IV and those undergoing emergency surgery

Where this trial is running

Aydin

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Postoperative Pain, Acuteadductor canal blockknee arthroplastyipack
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.