Adapting a behavioral activation program for minimally verbal autistic adults

Adaptation of a Behavioral Activation Treatment to Treat Depression in Autistic Adults

Not applicable Interventional Rutgers, The State University of New Jersey · NCT06064422

This study is testing a new program designed to help minimally verbal autistic adults who feel down by making sure it fits their needs and is easy for them to use.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment15 (estimated)
Ages18 Years and up
SexAll
SponsorRutgers, The State University of New Jersey Academic / other
Locations1 site (Piscataway, New Jersey)
Trial IDNCT06064422 on ClinicalTrials.gov

What this trial studies

This project aims to adapt the BeatIt-2 behavioral activation intervention specifically for minimally verbal autistic adults experiencing low mood. The first phase involves creating a tailored intervention manual with input from autistic individuals and their supporters. The second phase will conduct a feasibility trial to assess the acceptability and practicality of the adapted intervention. The study focuses on ensuring that the unique needs of this population are met through a collaborative approach.

Who should consider this trial

Good fit: Ideal candidates are minimally verbal adults aged 18 and older with a diagnosis of Autism Spectrum Disorder and clinically significant depression.

Not a fit: Patients who are not able to engage in treatment in English or are currently receiving other treatments for depression may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve the mental health and quality of life for minimally verbal autistic adults.

How similar studies have performed: While similar behavioral activation approaches have shown promise in other populations, this specific adaptation for minimally verbal autistic adults is novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Minimally verbal
* Aged 18 years or older
* Diagnosis of Autism Spectrum Disorder and clinically significant depression based on clinical best estimate diagnosis using DSM-5 or Diagnostic Manual - Intellectual Disability criteria
* Have a support person willing to participate
* Live in New Jersey or New York, or be within travel distance to Rutgers University

Exclusion Criteria:

* Not able to engage in treatment in English
* current engagement in other treatment for depression
* conditions that may preclude engagement in treatment sessions (e.g., active psychosis, unmanaged seizures)
* high suicide risk (i.e., with a clear plan, expressed intent or recent documented attempts)

Where this trial is running

Piscataway, New Jersey

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions AutismDepressionAutism Spectrum Disorder With Impaired Functional LanguageAutism Spectrum Disorderbehavioral activation
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.