Adapted physical activity program for people with hemophilia

Effectiveness of an Adapted Physical Activity Program for Subjects Suffering From Haemophilia:a Prospective Interventional Study

Not applicable Interventional Istituto Ortopedico Rizzoli · NCT06580340

This study tests a special exercise program for people with hemophilia to see if it helps them move better and feel stronger over six months.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment16 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorIstituto Ortopedico Rizzoli Academic / other
Locations1 site (Bologna, Bo)
Trial IDNCT06580340 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of a tailored physical activity program designed for individuals with hemophilia. The program consists of one-hour sessions held twice a week for six months, focusing on improving joint mobility, muscle strength, balance, and motor coordination. The primary outcome is the change in functional capacity, measured through the 6 Minutes Walking Test at baseline, 3 months, and 6 months using the G-Walk device.

Who should consider this trial

Good fit: Ideal candidates include individuals diagnosed with hemophilia A or B who can participate in non-competitive physical activities.

Not a fit: Patients with active bleeding, severe joint deformities, or significant cardiovascular and neurological conditions may not benefit from this program.

Why it matters

Potential benefit: If successful, this program could significantly enhance the physical capabilities and quality of life for patients with hemophilia.

How similar studies have performed: While similar approaches have been explored, this specific adaptation for hemophilia is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnosis of hemophilia A or B;
* Signature of informed consent;
* Availability of a medical certificate for non-competitive activities

Exclusion Criteria:

* Active bleeding
* Severe joint deformities that prevent exercise
* Insufficiency of communicative and/or sensory functions so severe that it is impossible to understand or carry out the trainer's instructions (dementia, aphasia, blindness, deafness)
* Heart failure (NYHA class \> 2)
* Unstable angina
* Lung disease requiring oxygen therapy
* Symptomatic peripheral arterial disease
* Myocardial infarction or hospitalization within the previous 6 months
* Symptomatic orthostatic hypotension
* Hypertension in poor pharmacological control (diastolic\> 95 mmHg, systolic\> 160 mmHg)
* Significant neurological conditions that impair motor or cognitive function

Where this trial is running

Bologna, Bo

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions HemophiliaSports Physical Therapy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.