Clinical trial Recruiting at 1 site Phase 2 Interventional Ages 18 to 65

Acupuncture with Chinese herbal cream versus acupuncture with calcipotriol for plaque psoriasis

Official title: Comparative Efficacy of Acupuncture Combined With Chinese Herbal Cream and Acupuncture Combined With Calcipotriol for Plaque Psoriasis.

Run by Mae Fah Luang University · NCT07410793 · Data updated 2026-11-12

This project will see if acupuncture plus a Chinese herbal cream works as well as acupuncture plus calcipotriol ointment for people with mild plaque psoriasis.

More Plaque Type Psorisis trials

Quick facts

PhasePhase 2
Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment28 (estimated)
SponsorMae Fah Luang University
Academic / other
Locations1 site (Muang, Chiangrai)
StatusRecruiting
StartedFebruary 9, 2026
Main results expectedFebruary 8, 2027
Study endsFebruary 8, 2027
Registry record updatedFebruary 13, 2026
Trial IDNCT07410793 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with mild plaque psoriasis (≤10% BSA, PASI ≤10, DLQI ≤10) who have not used psoriasis treatments for at least four weeks and who can undergo acupuncture are ideal candidates.

Probably not a fit

Patients with extensive or non-plaque forms of psoriasis, recent biologic or immunosuppressive therapy, pregnancy, anticoagulant use, needle phobia, or uncontrolled systemic disease are unlikely to benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This Phase 2 interventional study compares two combination treatments for plaque psoriasis: acupuncture with a topical Chinese herbal cream versus acupuncture with topical calcipotriol 0.005% ointment. Eligible adults have mild plaque psoriasis (≤10% body surface area, PASI ≤10, DLQI ≤10) and must be off other psoriasis treatments for at least four weeks. Participants are assigned to receive acupuncture together with one of the topical preparations and will have skin severity and quality-of-life measures recorded before and after the treatment period. The trial is conducted at Mae Fah Luang University in Chiangrai, Thailand, and excludes patients with non-plaque psoriasis types, major uncontrolled illnesses, recent biologic therapy, anticoagulant use, pregnancy, or needle phobia.

Why it matters

Potential benefit: If successful, this approach could offer an alternative topical option combined with acupuncture that improves skin symptoms and quality of life for patients with mild plaque psoriasis.

How similar studies have gone: Small trials and observational reports have shown mixed or limited benefits from acupuncture and topical herbal therapies for psoriasis, so this combined approach remains promising but not yet well proven.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Plaque psoriasis on skin, scalp, or nails
* Not receive any psoriasis treatment at least 4 weeks prior to the study
* ≤10% body surface area (BSA), PASI≤10, DLQI≤10

Exclusion Criteria:

* Pregnancy and lactation
* Other type of psoriasis i.e. Psoriatic arthritis, Pustular psoriasis, Erythrodermic psoriasis
* Uncontrollable diseases i.e. CVS, liver, kidney, cancer
* Using anticoagulants i.e. Aspirin, Warfarin, Clopidogrel, Dabigatran, Riavaraxaban, Apixaban, Heparin
* Treated with psoriasis biologic agents in the past 6 months
* Needle phobia
* Receiving immunosuppresive agents i.e. systemic corticosteroid, NSAIDs, chemotherapeutic agents
* Participating in other clinical study

Where it's running

  • Mae Fah Luang University
    Muang, Chiangrai, Thailand
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.