Acupuncture-style TENS to reduce pain and stress before and during egg retrieval
Official title: Acupuncture-type Transcutaneous Electrical Nerve Stimulation on Pain and Stress Reduction Before and During Transvaginal Ultrasound-guided Oocyte Retrieval: a Randomized Controlled Trial
Run by Chinese University of Hong Kong · NCT06910540 · Data updated 2026-11-12
This trial will test whether acupuncture-style transcutaneous electrical nerve stimulation (acu-TENS) can cut pain by half for women having transvaginal ultrasound-guided egg retrieval.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 144 (estimated) |
| Sponsor | Chinese University of Hong Kong Academic / other |
| Locations | 1 site (Hong Kong) |
| Status | Recruiting |
| Started | September 1, 2025 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2028 |
| Registry record updated | December 22, 2025 |
| Trial ID | NCT06910540 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women scheduled for transvaginal ultrasound-guided oocyte retrieval (IVF/ET cycles) who can consent and do not have major cardiac or respiratory disease and who are not current smokers or drinkers.
✕Probably not a fit
Patients with severe cardiac or respiratory disease, current smokers or drinkers, those ineligible for acu-TENS, or people unable to attend the Hong Kong site are unlikely to benefit from or be eligible for this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective randomized controlled trial at the Prince of Wales Hospital enrolling 144 women undergoing transvaginal ultrasound-guided oocyte retrieval who will be randomized to receive acu-TENS or a sham procedure during retrieval. Acu-TENS is delivered with a Myolito multifunctional stimulator while standard ultrasound-guided follicle aspiration is performed. The primary aim is to see if acu-TENS reduces procedural pain intensity by 50%, with pain measured during the procedure (detailed primary outcome specification not provided). The protocol excludes patients with severe cardiac or respiratory disease, current smoking or drinking, or inability/refusal to consent, and will record adverse events and postoperative pain or stress measures as secondary data.
Why it matters
Potential benefit: If successful, acu-TENS could substantially reduce pain and stress during egg retrieval and reduce reliance on other analgesics.
How similar studies have gone: Prior small studies of TENS and acupuncture-type approaches have shown benefits for some types of procedural and postoperative pain, but application specifically to transvaginal oocyte retrieval is limited and not widely confirmed.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women undergoing IVF-ET cycles are to be recruited from the Assisted Reproduction Technology unit in the Prince of Wales Hospital Exclusion Criteria: * Patient not eligible for acu-TENS * Patient with severe cardiac and respiratory disease history * Smoker or drinker * Refuse or incompetence for informed consent
Where it's running
-
Chung Pui Wah, Jacqueline
Hong Kong, China Recruiting
Study contacts
- Study coordinator: Pui Wah Jacqueline Chung
- Email: jacquelinechung@cuhk.edu.hk
- Phone: +852 3505 1537
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.