Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Acupoint herbal patching to relieve qi deficiency and constipation during chemotherapy

Official title: Clinical Study on Acupoint Application Based on the Theory of "State-target Syndrome Differentiation" in Relieving qi Deficiency and Constipation in Patients With Colorectal Cancer Undergoing Postoperative Chemotherapy

Run by Second Affiliated Hospital, Zhejiang University, School of Medicine · NCT07276932 · Data updated 2026-11-12

This trial tests whether applying herbal patches to acupuncture points can help adults with colorectal cancer who have qi deficiency and constipation while they receive postoperative chemotherapy.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment106 (estimated)
SponsorSecond Affiliated Hospital, Zhejiang University, School of Medicine
Academic / other
Drugs / interventionsChemotherapy
Locations1 site (Hangzhou, Zhejiang)
StatusRecruiting
StartedJuly 16, 2025
Main results expectedDecember 31, 2025
Study endsDecember 31, 2027
Registry record updatedDecember 11, 2025
Trial IDNCT07276932 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (age ≥18) with a clinical diagnosis of colorectal cancer who have had surgery, are receiving postoperative chemotherapy, and are diagnosed with qi deficiency and constipation are the intended participants.

Probably not a fit

Patients with other organic digestive or anal diseases, severe cardiac/hepatic/renal insufficiency, or known allergy to the constipation paste are unlikely to benefit or may be excluded.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers first developed a standardized acupoint application protocol for patients with qi deficiency and constipation using literature review and two rounds of Delphi expert consultation. They will conduct a randomized controlled trial comparing the acupoint application plus routine constipation care versus routine care alone in postoperative colorectal cancer patients receiving chemotherapy. Outcomes include constipation symptom relief, overall clinical efficacy, and patient comfort. The study excludes patients with other organic digestive diseases, severe organ failure, or allergy to the treatment and is conducted at a single center in Hangzhou, Zhejiang.

Why it matters

Potential benefit: If successful, this approach could reduce constipation symptoms and increase comfort for colorectal cancer patients undergoing chemotherapy.

How similar studies have gone: Some small studies of acupoint application or acupuncture for chemotherapy-related gastrointestinal symptoms have reported symptom improvement, but high-quality randomized evidence is still limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Clinical diagnosis of colorectal cancer
2. Chemotherapy was performed after surgery
3. Diagnosis of qi deficiency and constipation
4. Age ≥18 years old

Exclusion Criteria:

1. Clinical diagnosis of other digestive tract or anal organic diseases
2. Observed with severe cardiac, hepatic, renal insufficiency or other complications
3. Allergic constitution or allergy to a drug in constipation paste

Where it's running

  • The Second Affiliated Hospital of Zhejiang University School of Medicine
    Hangzhou, Zhejiang, China
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.