Active magnetically controlled capsule endoscopy for small bowel navigation
Official title: Active Locomotion of Magnetically Controlled Capsule Endoscopy With Small Bowel Insufflation or Water Infusion: A Feasibility Study
Run by Shandong University · NCT07325344 · Data updated 2026-11-12
We will test whether a handheld magnetic controller can steer a capsule endoscope through the small bowel in patients already scheduled for enteroscopy.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 15 (estimated) |
| Sponsor | Shandong University Academic / other |
| Locations | 1 site (Jinan, Shandong) |
| Status | Recruiting |
| Started | December 1, 2025 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | January 8, 2026 |
| Trial ID | NCT07325344 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients already scheduled for enteroscopy who can provide informed consent and do not have implanted electronic or metal devices, severe organ dysfunction, pregnancy, or contraindications to bowel preparation.
✕Probably not a fit
Patients with implanted pacemakers or metal implants, significant organ failure, small bowel obstruction, multiple prior major abdominal surgeries, pregnancy or lactation, or inability to consent are unlikely to benefit or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Patients undergoing double-balloon enteroscopy will have a magnetically controlled capsule introduced while the endoscopist uses standard air insufflation or water infusion. A handheld attitude controller will be used to attempt active locomotion of the capsule within the small bowel. Real-time video from both the enteroscope and the capsule will be recorded and compared to determine responsiveness and controllability. The trial is a feasibility interventional protocol to characterize how reliably the capsule follows magnetic steering during routine enteroscopy procedures.
Why it matters
Potential benefit: If successful, this approach could enable controlled navigation of capsule endoscopes to improve lesion localization and diagnostic yield in small bowel disease.
How similar studies have gone: Magnetically controlled capsule endoscopy has shown feasibility in gastric applications and some exploratory work in the small bowel, but combining handheld magnetic steering with simultaneous double-balloon enteroscopy imaging is relatively novel and primarily exploratory.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients scheduled to undergo enteroscopy. Exclusion Criteria: * Patients with severe dysfunction of vital organs (e.g., heart, lungs). Patients with small bowel obstruction precluding adequate bowel preparation. Patients with a history of multiple abdominal surgeries. Patients with implanted devices such as cardiac pacemakers or metal implants. Patients with other high-risk conditions or lesions (e.g., moderate-to-severe esophagogastric varices, massive ascites). Patients who are pregnant or lactating. Patients unable or unwilling to provide informed consent.
Where it's running
-
Qilu Hospital of Shandong University
Jinan, Shandong, China Recruiting
Study contacts
- Study coordinator: Xiuli Zuo, MD,PhD
- Email: zuoxiuli@sdu.edu.cn
- Phone: +86-18560080066
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.