Active Apex Correction for Early Onset Scoliosis in young children
Official title: Management of Early Onset Scoliosis by Active Apex Correction Technique
Run by Al-Azhar University · NCT07727408 · Data updated 2026-11-12
This trial tests a fusionless approach to guide the growth of the curve’s apex in children under 10 with early onset scoliosis to see if it improves spinal alignment and related outcomes.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 1 Year to 10 Years |
| Sex | All |
| Enrollment | 15 (estimated) |
| Sponsor | Al-Azhar University Academic / other |
| Locations | 1 site (Asyut, Asyut Governorate) |
| Status | Recruiting |
| Started | November 25, 2023 |
| Main results expected | October 11, 2026 |
| Study ends | January 2, 2027 |
| Registry record updated | July 27, 2026 |
| Trial ID | NCT07727408 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children under 10 with early onset scoliosis who have not previously undergone spinal surgery.
✕Probably not a fit
Patients beyond the age limit or those with prior spinal surgery may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study uses an apex-targeted tethering technique to modulate growth on the convex side of the spine and adjust the concave side in children under 10 who have not had prior surgery. The aim is to reduce curvature while allowing continued growth of the spine and lungs, potentially avoiding thoracic insufficiency syndrome. Outcomes will be tracked through radiological measurements and clinical assessments over follow-up visits. The study is conducted at Al-Azhar University Hospital in Assiut, with Al-Azhar University as the lead sponsor.
Why it matters
Potential benefit: If successful, the approach could reduce the need for more invasive fusion surgery and support growth of the spine and lungs.
How similar studies have gone: Fusionless growth-modulation strategies have shown variable success in EIS, with some positive radiographic changes in observational studies; this approach explores apex-targeted interference.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients with early-onset scoliosis below 10 years * patients not operated on before. Exclusion Criteria: * Patients above 10 years. * Patients operated on before
Where it's running
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Al-Azhar University Hospital, Assiut
Asyut, Asyut Governorate, Egypt Recruiting
Study contacts
- Study coordinator: mahmoud gaber
- Email: mahmoudgaber300@gmail.com
- Phone: +201094189506
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.