Acoustic stimulation treatment for chronic tinnitus

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional protocol delivers targeted acoustic stimulation to adults with chronic tinnitus and no structural ear lesions. Eligible participants must have had tinnitus for more than six months, be mentally stable, and be off other tinnitus treatments for at least three months. Patients with middle ear disease, temporal bone lesions, recent ototoxic drug exposure, or central nervous system disorders are excluded. Treatments and follow-up are conducted at a single center in Nanjing, with symptom changes used to judge effect.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with chronic tinnitus lasting over six months (with or without hearing loss), showing no organic lesions in the auditory conduction pathway or temporal bone, and either not receiving any treatment (including medication or traditional Chinese medicine) or having discontinued therapy for over three months. These patients must be mentally alert, mentally stable, and able to provide fluent responses to all questions from the doctor and research team members.

Exclusion Criteria:

* Patients with organic lesions in the auditory conduction pathway and temporal bone (e.g., tympanic membrane perforation, ossicular chain disruption), other otological conditions such as Meniere's disease, vertigo, chronic otitis media, middle ear cholesteatoma, or acute/chronic external otitis, history of head trauma or central nervous system disorders, exposure to ototoxic drugs, use of tinnitus medications or traditional Chinese medicine treatments (within 3 months of discontinuation), inability to cooperate with medical procedures or answer questions, or participants who dropped out or lost contact within 3 months.

Where it's running

• The First Affiliated Hospital with Nanjing Medical University
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Lei Cheng, PhD，MD
• Email: chenglei@jsph.org.cn
• Phone: +86 13776620807

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Neck nerve electrical stimulation combined with sound-frequency training for chronic tonal tinnitus

  This trial tests whether pairing a safe electrical stimulation of the greater occipital nerve with an active sound-frequency training task can reduce tinnitus loudness and distress in adults with chronic tonal tinnitus.

  Recruiting University of Dublin, Trinity College · Dublin, Dublin · NCT07393880

• Personalized-target transcranial magnetic stimulation for chronic tinnitus

  This trial will test whether TMS aimed at each person's auditory cortex using their resting-state MRI helps adults with chronic tinnitus more than standard TMS.

  Recruiting Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Guangzhou, Guangdong · NCT07267455

• Online Mindfulness-Based Cognitive Therapy for chronic tinnitus

  This trial tests a 6-week online MBCT program to see if it reduces tinnitus-related distress and the anxiety or depression that often comes with chronic tinnitus.

  Recruiting University of Warsaw · Warsaw · NCT07183826

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.