Access to a device for selecting stem cells for patients with poor graft function
Compassionate Access of the Miltenyi Device for CD34+ Cell Selection
NA · M.D. Anderson Cancer Center · NCT02438904
This study is testing a special device to help patients with poor graft function after a stem cell transplant by selecting and infusing specific stem cells to boost their immune system.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Sex | All |
| Sponsor | M.D. Anderson Cancer Center (other) |
| Locations | 1 site (Houston, Texas) |
| Trial ID | NCT02438904 on ClinicalTrials.gov |
What this trial studies
This study aims to provide compassionate access to the Miltenyi device for the infusion of CD34 positive stem cells in patients who have experienced poor graft function following stem cell transplantation. The process involves collecting stem cells from a donor's blood, selecting the necessary CD34 positive cells, and infusing them into the patient to help regenerate their immune system. Patients will receive pre-infusion medications to minimize side effects, and the infusion will take place in either an inpatient or outpatient setting. Monitoring will occur post-infusion to ensure patient safety.
Who should consider this trial
Good fit: Ideal candidates for this study are patients who have poor or no graft function following stem cell transplantation.
Not a fit: Patients who do not have issues with graft function post stem cell transplantation may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could improve immune system recovery in patients suffering from poor graft function after stem cell transplantation.
How similar studies have performed: Other studies have shown promise in using CD34 positive stem cell infusions for improving graft function, indicating that this approach has potential based on prior research.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1\) Patients who have poor or no graft function post stem cell transplantation. Exclusion Criteria: N/A
Where this trial is running
Houston, Texas
- University of Texas MD Anderson Cancer Center — Houston, Texas, United States (RECRUITING)
Study contacts
- Principal investigator: Elizabeth Shpall, MD — M.D. Anderson Cancer Center
- Study coordinator: Elizabeth Shpall, MD
- Email: eshpall@mdanderson.org
- Phone: 713-745-2161
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Blood And Marrow Transplantation, Stem cell transplantation, SCT, Poor graft function, CD34+ cell infusion