Acceptance and Commitment Therapy to reduce cancer distress in hepatobiliary cancer patients
Official title: Development of Acceptance and Commitment Therapy for Cancer Distress Among Rural and Urban Patients With Incurable Cancers (ACT-C)
Run by Mayo Clinic · NCT07124546 · Data updated 2026-11-12
This project tests if Acceptance and Commitment Therapy (ACT) helps adults with hepatobiliary cancer reduce cancer-related distress.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Mayo Clinic Academic / other |
| Locations | 1 site (Rochester, Minnesota) |
| Status | Recruiting |
| Started | May 28, 2025 |
| Main results expected | May 30, 2027 |
| Study ends | May 30, 2027 |
| Registry record updated | August 4, 2026 |
| Trial ID | NCT07124546 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18) with active hepatobiliary cancer who verbally report cancer distress, can read and write English, have internet access, and live in Iowa, Minnesota, or Wisconsin are ideal candidates.
✕Probably not a fit
Patients in HBC remission, those without significant cancer distress, those lacking internet access or English literacy, and those with active uncontrolled psychosis or a very recent new psychological therapy may not benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional program delivers Acceptance and Commitment Therapy tailored for patients with hepatobiliary cancers, primarily via telemedicine. Participants complete standardized questionnaires before, during, and after the intervention to measure cancer distress and related quality-of-life outcomes. Eligible adults must report cancer-related distress, be able to read and write English, have internet access, and reside in Iowa, Minnesota, or Wisconsin. Patients with HBC in remission, uncontrolled psychotic symptoms, or who recently started another psychological therapy are excluded.
Why it matters
Potential benefit: If successful, this intervention could reduce cancer-related distress and improve patients' coping and quality of life.
How similar studies have gone: Acceptance and Commitment Therapy and other behavioral interventions have shown benefit for distress in oncology and chronic illness populations, but ACT specifically tailored for hepatobiliary cancer is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Incurable HBC and breast cancer diagnosis * Age \>= 18 years * Able to provide written informed consent * Verbally endorse cancer distress * Access to the internet * Read and write in English * Reside in the states of Minnesota Exclusion Criteria: * Other psychological therapy that started =\< 2 months prior to prospective enrollment * Inability to actively participate in and learn from group therapy (e.g., active/uncontrolled psychotic symptoms, neurological condition, personality pathology) as determined by clinical judgement in Behavioral Medicine Program (BMP) consultation. Individual therapy or alternative group therapy will be offered to patients ineligible per this criterion * Cancer remission
Where it's running
-
Mayo Clinic in Rochester
Rochester, Minnesota, United States Recruiting
Study contacts
- Principal investigator: Carrie A Bronars, PhD, LP — Mayo Clinic in Rochester
- Study coordinator: Sofia Hammel
- Email: Hammel.Sofia@mayo.edu
- Phone: 507-255-0760
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.