Clinical trial Recruiting at 1 site Interventional Ages 35 to 54

Acapella vs Flutter for breathing after lobectomy

Official title: Comparative Effects of Acapella and Flutter Devices on Secretion Clearance, Dyspnea, Arterial Blood Gases, and Lung Function Test in Post-Lobectomy Patients

Run by Riphah International University · NCT07737093 · Data updated 2026-11-12

In people who have had a lobectomy, this study tests whether the Acapella device or the Flutter device helps clear mucus and improve breathing.

Quick facts

Study typeInterventional
Ages35 Years to 54 Years
SexAll
Enrollment28 (estimated)
SponsorRiphah International University
Academic / other
Locations1 site (Lahore, Punjab Province)
StatusRecruiting
StartedJune 20, 2026
Main results expectedNovember 15, 2026
Study endsDecember 15, 2026
Registry record updatedJuly 30, 2026
Trial IDNCT07737093 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 35-54 who recently underwent lobectomy, are hemodynamically stable, can maintain oxygenation, and are able to perform breathing exercises with the devices.

Probably not a fit

Patients who are unstable, cannot perform the breathing exercises, or have contraindications to airway clearance techniques may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two oscillatory positive expiratory pressure devices—Acapella and Flutter—in post-lobectomy patients. Participants are 35 to 54 years old and are 48 hours post-surgery with stable respiratory function. The study will assess secretion clearance, dyspnea, arterial blood gases, and measures of lung function to determine which device provides better short-term pulmonary recovery. It aims to inform postoperative airway clearance strategies in lobectomy care. The trial is conducted at Riphah International University in Lahore, Pakistan.

Why it matters

Potential benefit: If successful, patients may experience better mucus clearance and faster improvement in breathing after lobectomy.

How similar studies have gone: Previous research supports the benefits of OPEP devices in respiratory recovery, but direct head-to-head comparison in lobectomy patients is limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients aged 35 to 54 years
* Both male and female patients
* Patients who have undergone lobectomy surgery
* Hemodynamically stable patients
* Patients with adequate respiratory function (able to maintain oxygenation)
* Patients 48 hours post-surgery
* Patients who provide written informed consent to participate in the study

Exclusion Criteria:

* Hemodynamically unstable patients
* Patients within less than 48 hours post-surgery
* Presence of pneumothorax or air leak complications
* Patients with recent major trauma or additional surgery
* Patients with unstable cardiac conditions
* Patients with massive hemoptysis
* Patients unable to cooperate or perform breathing exercises with devices
* Any contraindication to airway clearance techniques as judged by the clinician

Where it's running

  • Riphah International University
    Lahore, Punjab Province, Pakistan
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.