A new treatment model for elderly lung cancer patients
Official title: A Multicenter Clinical Study on a New Treatment Model Combining New Surgical Techniques, Perioperative Comprehensive Treatment, and Postoperative Rehabilitation for Elderly Patients With Lung Cancer
Run by Peking University People's Hospital · NCT07632664 · Data updated 2026-11-12
This trial tests a comprehensive, integrated care approach for older adults with lung cancer to improve perioperative management and outcomes.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 65 Years and up |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | Peking University People's Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | August 1, 2024 |
| Main results expected | December 30, 2026 |
| Study ends | August 31, 2028 |
| Registry record updated | July 15, 2026 |
| Trial ID | NCT07632664 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients aged 65 or older with pathologically confirmed non-small cell lung cancer eligible for curative resection who have complete preoperative geriatric assessment data and can undergo planned surgery and long-term follow-up.
✕Probably not a fit
Patients who have distant metastasis, severe contraindications to thoracic surgery, or unwillingness to participate in randomization and follow-up may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This multicenter prospective study aims to develop and validate a full-cycle, risk-stratified treatment model for elderly lung cancer patients. It includes building a large clinical registry, creating perioperative risk stratification and early-warning tools, optimizing surgical strategies based on patient risk, and delivering multidisciplinary, integrated Chinese-Western medicine care with personalized postoperative rehabilitation. The study plans to enroll over 2,000 patients across at least 30 centers and to evaluate outcomes such as complications, overall and disease-free survival, and treatment-related adverse events. It compares different surgical approaches—radical resection, precise limited resection, and palliative resection—guided by the risk stratification system. The project emphasizes standardized data collection, external validation, and long-term follow-up to form an optimized, whole-cycle treatment model for elderly lung cancer patients.
Why it matters
Potential benefit: If successful, patients could experience safer surgeries, fewer complications, and improved long-term outcomes through personalized, comprehensive perioperative care.
How similar studies have gone: Prior work in perioperative risk stratification and multidisciplinary, integrated care has shown promise; this study extends those concepts to a large, multicenter elderly lung cancer population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Aged ≥65 years old 2. Pathologically confirmed non-small cell lung cancer with clinical stage eligible for curative surgical resection 3. Complete preoperative geriatric comprehensive assessment data available 4. Capable of finishing planned surgery and long-term follow-up 5. Voluntarily sign informed consent form Exclusion Criteria: 1. History of other malignant tumors within recent 5 years 2. Severe organic dysfunction of heart, liver, renal or respiratory system that cannot tolerate thoracic surgery 3. Preoperative confirmed distant metastasis preventing radical resection 4. Uncontrolled active severe infection or obvious coagulation disorders 5. Severe psychiatric disorder or cognitive dysfunction failing to cooperate with treatment and follow-up 6. Refuse random grouping and postoperative regular monitoring
Where it's running
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Peking University People's Hospital
Beijing, Beijing Municipality, China Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.