Clinical trial Recruiting at 1 site Interventional Ages 18 to 110

A long-term project to improve brain health and performance

Official title: The BrainHealth Project, a Longitudinal Study in Generally Healthy Adults

Run by The University of Texas at Dallas · NCT04869111 · Data updated 2026-11-12

This study is testing ways to improve brain health and thinking skills over ten years by checking in with participants regularly and offering online training and coaching.

Quick facts

Study typeInterventional
Ages18 Years to 110 Years
SexAll
Enrollment100000 (estimated)
SponsorThe University of Texas at Dallas
Academic / other
Locations1 site (Dallas, Texas)
StatusRecruiting
StartedAugust 1, 2020
Main results expectedAugust 1, 2038
Study endsAugust 1, 2038
Registry record updatedJune 23, 2026
Trial IDNCT04869111 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are English-speaking individuals with internet access who are interested in optimizing their brain health.

Probably not a fit

Patients with diagnosed neurodegenerative diseases or significant brain injuries may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The BrainHealth Project is a ten-year longitudinal initiative aimed at identifying factors that influence brain health and cognitive performance. Participants will engage in semi-annual online assessments to monitor their cognitive function over time, complemented by access to online training and resources designed to enhance brain health. Additionally, one-on-one coaching sessions will be available to support participants in applying learned strategies to their daily lives. A select group will also have the opportunity to participate in brain imaging assessments to further explore brain health determinants.

Why it matters

Potential benefit: If successful, this project could lead to improved strategies for maintaining and enhancing cognitive function across the lifespan.

How similar studies have gone: While there have been various studies on cognitive health, this project's comprehensive approach to long-term brain health optimization is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* English-speaking
* Access to an internet connect and device
* Able to read information and hear sounds

Exclusion Criteria:

* Diagnosed neurodegenerative disease
* History of stroke, concussion, or brain injury that currently hinders you from functioning at your prior level
* Diagnosed with Autism Spectrum Disorder and not functioning independently

For an overview of the study and LINK TO REGISTER please go to -- https://brainhealth.utdallas.edu/programs/the-brainhealth-project/

Where it's running

  • The Center for BrainHealth at The University of Texas at Dallas
    Dallas, Texas, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.