A hospital biobank of leftover clinical samples to support rapid diagnostic tests for emerging infectious threats.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The DiagRaMIE Biobank is a multicenter prospective registry that systematically collects leftover clinical specimens (blood, serum, plasma, respiratory samples, urine, cerebrospinal fluid, biopsies) and linked pseudonymized clinical and microbiological data from hospitalized adults at Bicêtre and Paul Brousse over a three-year inclusion period. No extra procedures or visits are required; samples obtained during routine care are stored securely for up to 20 years. The resource is intended to support development and validation of in vitro rapid diagnostic tests for emerging infectious diseases and CBRN threats, including WHO-prioritized pathogens. Data and specimens will be accessible to qualified developers and researchers to accelerate test evaluation and strengthen epidemic preparedness and patient management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults (≥ 18 years old) hospitalized in one of the participating centers at Bicêtre or Paul Brousse hospitals, for whom residual biological samples are available as part of routine care in one or more participating hospital departments.
* Covered by, or entitled to, the French social security system (excluding State Medical Aid - AME).
* Patient or legal representative/trusted person informed about the registry and having provided written consent to participate.

Exclusion Criteria:

* Patients under judicial protection (guardianship or curatorship).
* Patients deprived of liberty by judicial or administrative decision.
* Patients not speaking French and not accompanied by a translator.

Where it's running

• CHU Bicêtre
  Le Kremlin-Bicêtre, France Recruiting
• CHU Bicêtre
  Le Kremlin-Bicêtre, France Recruiting
• CHU Bicêtre
  Le Kremlin-Bicêtre, France Recruiting
• CHU Bicêtre
  Le Kremlin-Bicêtre, France Recruiting
• CHU Bicêtre
  Le Kremlin-Bicêtre, France Recruiting
• CHU Bicêtre
  Le Kremlin-Bicêtre, France Recruiting

Study contacts

• Study coordinator: Thierry NAAS,, PhD
• Email: thierry.naas@aphp.fr
• Phone: 1 45 21 29 86

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.