A database to understand von Hippel-Lindau Disease and related conditions

MyVHL: Patient Natural History Study

Observational VHL Alliance · NCT03749980

This study is creating a database to see how lifestyle and other factors affect people with von Hippel-Lindau Disease and similar conditions, helping researchers find better treatments and understand the disease better.

Quick facts

Study typeObservational
Enrollment10000 (estimated)
SexAll
SponsorVHL Alliance Academic / other
Locations1 site (Boston, Massachusetts)
Trial IDNCT03749980 on ClinicalTrials.gov

What this trial studies

MyVHL is an observational study that creates a multi-patient database to identify patterns among individuals with von Hippel-Lindau Disease and related conditions. Participants provide information about their lifestyle, medications, and other factors that may influence their disease and quality of life. This data helps researchers uncover risk factors, understand tumor growth, and potentially identify effective treatments. The study aims to enhance knowledge about these rare conditions and guide future research efforts.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with von Hippel-Lindau Disease.

Not a fit: Patients without a diagnosis of von Hippel-Lindau Disease or related conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of von Hippel-Lindau Disease and related conditions.

How similar studies have performed: While this approach is focused on a rare condition, similar observational studies have successfully contributed to understanding other rare diseases.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients with von Hippel-Lindau Disease (VHL)

Exclusion Criteria:

\-

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Von Hippel-Lindau DiseaseHereditary Leiomyomatosis and Renal Cell CancerBirt-Hogg-Dube SyndromeSDHB Gene MutationVHLBHDHLRCCSDHB
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.