A cohort for evaluating breast cancer treatments and outcomes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The UMBRELLA Cohort aims to create a prospective cohort of breast cancer patients undergoing irradiation at UMC Utrecht to evaluate various experimental interventions and their long-term effects. Utilizing a cohort multiple Randomized Controlled Trial (cmRCT) design, this study seeks to enhance recruitment and comparability while assessing treatment toxicity, quality of life, and cosmetic outcomes. By collecting clinical data and patient-reported outcomes through questionnaires, the study will provide a robust infrastructure for future evaluations of breast cancer interventions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* Patients with breast cancer who undergo irradiation in the UMC Utrecht
* Informed consent - at least - for use of routinely collected clinical data and to fill out questionnaires.

Exclusion Criteria:

* Inability to understand the Dutch language

Where it's running

• Ziekenhuisgroep Twente
  Almelo, Netherlands Recruiting
• Alrijne Ziekenhuis
  Leiderdorp, Netherlands Recruiting
• St. Antonius Ziekenhuis
  Nieuwegein, Netherlands Recruiting
• University Medical Center Utrecht
  Utrecht, Netherlands Recruiting

Study contacts

• Principal investigator: Helena M Verkooijen, MD, PhD — UMC Utrecht
• Study coordinator: Helena M Verkooijen, MD, PhD
• Email: h.m.verkooijen@umcutrecht.nl

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.