A brief intervention to help regular cannabis users manage stress

Refinement and Testing of a Brief Computerized and Smart Phone-based Intervention for Stress in Regular Cannabis Users

Not applicable Interventional Florida State University · NCT06085222

This study is testing a short, online program to help regular cannabis users manage their stress better and reduce their cannabis use.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages18 Years to 30 Years
SexAll
SponsorFlorida State University Academic / other
Locations1 site (Tallahassee, Florida)
Trial IDNCT06085222 on ClinicalTrials.gov

What this trial studies

This project evaluates a condensed, one-session computerized intervention aimed at reducing distress intolerance in individuals with Cannabis Use Disorder (CUD). The intervention incorporates an imaginal exposure module designed to enhance emotional engagement and utilizes just-in-time text message reminders based on real-time distress reports. By optimizing an existing intervention, the study seeks to assess its effectiveness in improving emotional regulation and reducing cannabis use outcomes through a randomized controlled trial. The approach is intended to be accessible and low-cost, targeting a high-risk population for significant public health impact.

Who should consider this trial

Good fit: Ideal candidates are individuals with a current diagnosis of Cannabis Use Disorder who use cannabis nearly daily and exhibit clinical-level distress intolerance.

Not a fit: Patients with acute psychiatric disturbances, those currently pregnant, or individuals planning to quit cannabis immediately may not benefit from this intervention.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce cannabis use and improve emotional regulation for individuals struggling with Cannabis Use Disorder.

How similar studies have performed: Other studies have shown promise with similar computerized interventions for substance use disorders, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Cannabis is the primary substance of abuse.
* Clinical-level Distress intolerance Index score.
* Current Cannabis Use Disorder diagnosis.
* Near-daily to daily cannabis use in past-month and past 3 months.
* Positive urine screen for THC
* Detectable skin conductance level
* Owns a smart phone
* Primary smoked/vaporized delta-9 or delta-8 THC user

Exclusion Criteria:

* Presence of acute/major psychiatric disturbance
* Current pregnancy
* Change in psychotropic medication within the past month
* Concurrently receiving treatment for cannabis use
* Concurrently receiving dialectical behavior therapy or exposure-based therapy for emotional disorders
* Planning to immediately quit using cannabis
* EEG contraindications
* Kidney disease

Where this trial is running

Tallahassee, Florida

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cannabis Use Disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.