5-Week Balanced Progressive Intensity Training (BPIT) for movement efficiency, mobility, and neuromuscular adaptation
Balanced Progressive Intensity Training (BPIT): A Five-Week Multi-Site Clinical Evaluation of Functional Movement, Mobility, and Neuromuscular Adaptation in Healthy Adults (18-65 Years)
NA · MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. · NCT07256717
This 5-week supervised program tests whether BPIT can improve movement efficiency, joint mobility, strength, postural control, and heart-rate variability in healthy adults aged 18–65.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 369 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. (other) |
| Locations | 10 sites (Columbus, Ohio and 9 other locations) |
| Trial ID | NCT07256717 on ClinicalTrials.gov |
What this trial studies
This single-arm, prospective, multi-site interventional protocol enrolls healthy adults aged 18–65 to complete supervised BPIT sessions 3–5 times per week for five weeks. Training progresses through five intensity "lines"—ground-based, knee-level, standing, head-level, and plyometric—defined by anatomical landmarks and ground reaction force. Primary endpoints are change in Functional Movement Screen (FMS) total score and Y‑Balance Test composite reach distance, with secondary measures including estimated 1‑RM strength, resting HRV (RMSSD), joint range of motion, postural sway, and incidence of training-related discomfort. Safety and individual overload indicators are monitored weekly at multiple sites in India and the United States.
Who should consider this trial
Good fit: Ideal candidates are generally healthy adults aged 18–65 with a recent history of regular exercise who can commit to 3–5 supervised sessions per week and have no acute injury or contraindicating medical conditions.
Not a fit: People with recent musculoskeletal injury (<3 months), known cardiovascular, metabolic or orthopedic contraindications, pregnancy, or inability to attend the required supervised sessions are unlikely to benefit from or be eligible for this program.
Why it matters
Potential benefit: If successful, the program could offer a structured, progressive exercise approach to measurably improve movement efficiency, mobility, strength, and autonomic recovery in recreationally active adults.
How similar studies have performed: Progressive loading and plyometric programs have previously improved strength, balance, and movement metrics, but the specific BPIT 5-Line framework is a novel, formally untested protocol at scale.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18-65 years Generally healthy with regular physical activity history (at least 1-2 sessions per week for the past 3 months) Able to commit to 3-5 supervised training sessions per week for 5 weeks Willing and able to provide written informed consent Cleared by pre-screening (no acute injury, no contraindications) Exclusion Criteria: * Acute musculoskeletal injury within the past 3 months Known cardiovascular, metabolic, or orthopaedic conditions that contraindicate exercise Pregnancy or planning pregnancy Use of medications or supplements that significantly affect muscle recovery or performance (e.g., corticosteroids, anabolic agents) Inability to follow the BPIT protocol or attend required sessions
Where this trial is running
Columbus, Ohio and 9 other locations
- BodyGNTX Fitness Institute — Columbus, Ohio, United States (RECRUITING)
- MMSx Authority Biomechanics Department — Powell, Ohio, United States (RECRUITING)
- MMSx AUTHORITY INSTITUTE FOR MOVEMENT MECHANICS & BIOMECHANICS RESEARCH (COORDINATING CENTER) — Powell, Ohio, United States (RECRUITING)
- Indian Institute of Kinesiology & Biomechanics Science (IIKBS) — Burhānpur, Madhya Pradesh, India (RECRUITING)
- Shri Mahaveer Ortho Clinic — Delhi, National Capital Territory of Delhi, India (RECRUITING)
- GFFI Fitness Academy — New Delhi, National Capital Territory of Delhi, India (RECRUITING)
- Active India Health & Fitness Trust (AIHFT) — New Delhi, National Capital Territory of Delhi, India (RECRUITING)
- Body Mechanics Gym P Ltd — New Delhi, National Capital Territory of Delhi, India (RECRUITING)
- Regain Fitness Zone — Greater Noida, Uttar Pardesh, India (RECRUITING)
- GFFI Fitness Academy — Agra, Uttar Pradesh, India (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Physical Fitness, Balanced Progressive Intensity Training, BPIT, 5-Line Principle, Movement Efficiency, Heart Rate Variability, Postural Control, Strength Training