Clinical trial Recruiting at 10 sites Interventional Ages 18 to 65

5-Week Balanced Progressive Intensity Training (BPIT) for movement efficiency, mobility, and neuromuscular adaptation

Official title: Balanced Progressive Intensity Training (BPIT): A Five-Week Multi-Site Clinical Evaluation of Functional Movement, Mobility, and Neuromuscular Adaptation in Healthy Adults (18-65 Years)

Run by MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. · NCT07256717 · Data updated 2026-11-12

This 5-week supervised program tests whether BPIT can improve movement efficiency, joint mobility, strength, postural control, and heart-rate variability in healthy adults aged 18–65.

Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment369 (estimated)
SponsorMMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.
Academic / other
Locations10 sites (Columbus, Ohio and 9 other locations)
StatusRecruiting
StartedOctober 10, 2025
Main results expectedFebruary 15, 2026
Study endsFebruary 25, 2026
Registry record updatedDecember 16, 2025
Trial IDNCT07256717 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are generally healthy adults aged 18–65 with a recent history of regular exercise who can commit to 3–5 supervised sessions per week and have no acute injury or contraindicating medical conditions.

Probably not a fit

People with recent musculoskeletal injury (<3 months), known cardiovascular, metabolic or orthopedic contraindications, pregnancy, or inability to attend the required supervised sessions are unlikely to benefit from or be eligible for this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-arm, prospective, multi-site interventional protocol enrolls healthy adults aged 18–65 to complete supervised BPIT sessions 3–5 times per week for five weeks. Training progresses through five intensity "lines"—ground-based, knee-level, standing, head-level, and plyometric—defined by anatomical landmarks and ground reaction force. Primary endpoints are change in Functional Movement Screen (FMS) total score and Y‑Balance Test composite reach distance, with secondary measures including estimated 1‑RM strength, resting HRV (RMSSD), joint range of motion, postural sway, and incidence of training-related discomfort. Safety and individual overload indicators are monitored weekly at multiple sites in India and the United States.

Why it matters

Potential benefit: If successful, the program could offer a structured, progressive exercise approach to measurably improve movement efficiency, mobility, strength, and autonomic recovery in recreationally active adults.

How similar studies have gone: Progressive loading and plyometric programs have previously improved strength, balance, and movement metrics, but the specific BPIT 5-Line framework is a novel, formally untested protocol at scale.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18-65 years Generally healthy with regular physical activity history (at least 1-2 sessions per week for the past 3 months) Able to commit to 3-5 supervised training sessions per week for 5 weeks Willing and able to provide written informed consent Cleared by pre-screening (no acute injury, no contraindications)

Exclusion Criteria:

* Acute musculoskeletal injury within the past 3 months Known cardiovascular, metabolic, or orthopaedic conditions that contraindicate exercise Pregnancy or planning pregnancy Use of medications or supplements that significantly affect muscle recovery or performance (e.g., corticosteroids, anabolic agents) Inability to follow the BPIT protocol or attend required sessions

Where it's running

  • BodyGNTX Fitness Institute
    Columbus, Ohio, United States
    Recruiting
  • MMSx Authority Biomechanics Department
    Powell, Ohio, United States
    Recruiting
  • MMSx AUTHORITY INSTITUTE FOR MOVEMENT MECHANICS & BIOMECHANICS RESEARCH (COORDINATING CENTER)
    Powell, Ohio, United States
    Recruiting
  • Indian Institute of Kinesiology & Biomechanics Science (IIKBS)
    Burhānpur, Madhya Pradesh, India
    Recruiting
  • Shri Mahaveer Ortho Clinic
    Delhi, National Capital Territory of Delhi, India
    Recruiting
  • GFFI Fitness Academy
    New Delhi, National Capital Territory of Delhi, India
    Recruiting
Show 4 more locations
  • Active India Health & Fitness Trust (AIHFT)
    New Delhi, National Capital Territory of Delhi, India
    Recruiting
  • Body Mechanics Gym P Ltd
    New Delhi, National Capital Territory of Delhi, India
    Recruiting
  • Regain Fitness Zone
    Greater Noida, Uttar Pardesh, India
    Recruiting
  • GFFI Fitness Academy
    Agra, Uttar Pradesh, India
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.