5-Week Balanced Progressive Intensity Training (BPIT) for movement efficiency, mobility, and neuromuscular adaptation
Official title: Balanced Progressive Intensity Training (BPIT): A Five-Week Multi-Site Clinical Evaluation of Functional Movement, Mobility, and Neuromuscular Adaptation in Healthy Adults (18-65 Years)
Run by MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. · NCT07256717 · Data updated 2026-11-12
This 5-week supervised program tests whether BPIT can improve movement efficiency, joint mobility, strength, postural control, and heart-rate variability in healthy adults aged 18–65.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 369 (estimated) |
| Sponsor | MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc. Academic / other |
| Locations | 10 sites (Columbus, Ohio and 9 other locations) |
| Status | Recruiting |
| Started | October 10, 2025 |
| Main results expected | February 15, 2026 |
| Study ends | February 25, 2026 |
| Registry record updated | December 16, 2025 |
| Trial ID | NCT07256717 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are generally healthy adults aged 18–65 with a recent history of regular exercise who can commit to 3–5 supervised sessions per week and have no acute injury or contraindicating medical conditions.
✕Probably not a fit
People with recent musculoskeletal injury (<3 months), known cardiovascular, metabolic or orthopedic contraindications, pregnancy, or inability to attend the required supervised sessions are unlikely to benefit from or be eligible for this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This single-arm, prospective, multi-site interventional protocol enrolls healthy adults aged 18–65 to complete supervised BPIT sessions 3–5 times per week for five weeks. Training progresses through five intensity "lines"—ground-based, knee-level, standing, head-level, and plyometric—defined by anatomical landmarks and ground reaction force. Primary endpoints are change in Functional Movement Screen (FMS) total score and Y‑Balance Test composite reach distance, with secondary measures including estimated 1‑RM strength, resting HRV (RMSSD), joint range of motion, postural sway, and incidence of training-related discomfort. Safety and individual overload indicators are monitored weekly at multiple sites in India and the United States.
Why it matters
Potential benefit: If successful, the program could offer a structured, progressive exercise approach to measurably improve movement efficiency, mobility, strength, and autonomic recovery in recreationally active adults.
How similar studies have gone: Progressive loading and plyometric programs have previously improved strength, balance, and movement metrics, but the specific BPIT 5-Line framework is a novel, formally untested protocol at scale.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18-65 years Generally healthy with regular physical activity history (at least 1-2 sessions per week for the past 3 months) Able to commit to 3-5 supervised training sessions per week for 5 weeks Willing and able to provide written informed consent Cleared by pre-screening (no acute injury, no contraindications) Exclusion Criteria: * Acute musculoskeletal injury within the past 3 months Known cardiovascular, metabolic, or orthopaedic conditions that contraindicate exercise Pregnancy or planning pregnancy Use of medications or supplements that significantly affect muscle recovery or performance (e.g., corticosteroids, anabolic agents) Inability to follow the BPIT protocol or attend required sessions
Where it's running
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BodyGNTX Fitness Institute
Columbus, Ohio, United States Recruiting -
MMSx Authority Biomechanics Department
Powell, Ohio, United States Recruiting -
MMSx AUTHORITY INSTITUTE FOR MOVEMENT MECHANICS & BIOMECHANICS RESEARCH (COORDINATING CENTER)
Powell, Ohio, United States Recruiting -
Indian Institute of Kinesiology & Biomechanics Science (IIKBS)
Burhānpur, Madhya Pradesh, India Recruiting -
Shri Mahaveer Ortho Clinic
Delhi, National Capital Territory of Delhi, India Recruiting -
GFFI Fitness Academy
New Delhi, National Capital Territory of Delhi, India Recruiting
Show 4 more locations
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Active India Health & Fitness Trust (AIHFT)
New Delhi, National Capital Territory of Delhi, India Recruiting -
Body Mechanics Gym P Ltd
New Delhi, National Capital Territory of Delhi, India Recruiting -
Regain Fitness Zone
Greater Noida, Uttar Pardesh, India Recruiting -
GFFI Fitness Academy
Agra, Uttar Pradesh, India Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.