3D ultrasound versus hysteroscopy for perimenopausal bleeding
Official title: Three Dimensional Ultrasonography Versus Hysteroscopy for the Evaluation of Patients With Perimenopausal Bleeding
Run by Sohag University · NCT07309692 · Data updated 2026-11-12
This compares 3D ultrasound and hysteroscopy to see which better finds the cause of abnormal uterine bleeding in women aged 40–55 during the perimenopausal period.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years to 55 Years |
| Sex | Women only |
| Enrollment | 106 (estimated) |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Status | Recruiting |
| Started | December 1, 2025 |
| Main results expected | August 31, 2026 |
| Study ends | August 31, 2026 |
| Registry record updated | December 30, 2025 |
| Trial ID | NCT07309692 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 40–55 with abnormal uterine bleeding (menorrhagia or metrorrhagia) lasting more than three months, without ovarian lesions or local vaginal/cervical causes, and not using hormonal therapy or an IUD.
✕Probably not a fit
Women who are postmenopausal, pregnant, have systemic conditions causing bleeding (such as diabetes, hypertension, or chronic liver disease), are on hormonal therapy or using an IUD, or have contraindications to hysteroscopy (for example cervical stenosis) are excluded and unlikely to benefit from this comparison.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Women aged 40–55 with at least three months of abnormal uterine bleeding will undergo evaluation using three-dimensional transvaginal ultrasonography and hysteroscopy. Investigators will compare the imaging and procedural findings to determine how well 3D ultrasound detects intrauterine causes of bleeding relative to hysteroscopy. The protocol excludes postmenopausal women, those with systemic causes of bleeding, current hormonal therapy or intrauterine devices, pregnancy, or contraindications to hysteroscopy. The study is conducted at Sohag University and uses the two modalities to directly compare diagnostic findings in the same clinical population.
Why it matters
Potential benefit: If successful, this could allow more cases to be diagnosed using a less invasive and quicker 3D ultrasound exam, reducing the need for invasive hysteroscopy in some patients.
How similar studies have gone: Previous work shows transvaginal and 3D ultrasound can detect many intrauterine abnormalities, but hysteroscopy remains the diagnostic reference standard.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Any pattern of abnormal uterine bleeding as menorrhagia or metrorrhagia for more than 3 months at age between 40 and 55 years , and no ovarian lesion or local cause of bleeding as vaginal or cervical ulcer Exclusion Criteria: * • Women with postmenopausal bleeding. * Systemic causes of perimenopausal bleeding DM Hypertension or chronic liver disease. * Women on hormonal therapy or using any contraception as IUD. * Women have contraindication for hysteroscopy as cervical stenosis or pregnancy.
Where it's running
-
Sohag University
Sohag, Egypt Recruiting
Study contacts
- Study coordinator: ahmed abdelrahem fattouh, resident of Obstetrics and Gyn
- Email: ahmedalatoon04@gmail.com
- Phone: 00201146329946
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.