Clinical trial Recruiting at 1 site Interventional Ages 18 to 60

3D-printed resin versus zirconia for implant crowns and short bridges in the lower front jaw

Official title: Clinical Performance of 3D-Printed Resin Versus Milled Monolithic Zirconia in Implant-Supported Single Crowns and Short-Span Fixed Partial Dentures: A Randomized Controlled Clinical Trial

Run by Menoufia University · NCT07522671 · Data updated 2026-11-12

This trial tests whether 3D-printed permanent resin crowns and short fixed bridges work as well as milled zirconia for adults needing one or two implants in the lower front jaw.

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Quick facts

Study typeInterventional
Ages18 Years to 60 Years
SexAll
Enrollment60 (estimated)
SponsorMenoufia University
Academic / other
Locations1 site (Shibīn al Kawm)
StatusRecruiting
StartedApril 1, 2026
Main results expectedApril 1, 2027
Study endsNovember 1, 2028
Registry record updatedApril 13, 2026
Trial IDNCT07522671 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (≥18 years) who have one or two osseointegrated implants in the mandibular anterior region with stable peri-implant tissues, good oral hygiene, and need a single implant crown or a short (≤3-unit) implant-supported bridge are ideal candidates.

Probably not a fit

Patients with severe parafunctional habits (e.g., bruxism), uncontrolled systemic conditions affecting bone healing, peri-implantitis or unstable implants, or those needing long-span or non-mandibular-anterior prostheses are unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, parallel-arm clinical trial comparing 3D-printed permanent resin (CROWNTEC) restorations to conventionally milled monolithic zirconia for implant-supported single crowns and short-span fixed partial dentures in the mandibular anterior region. All prostheses are produced using a standardized fully digital workflow (intraoral scanning, CAD design, and controlled fabrication) and delivered as screw- or cement-retained restorations. Participants are followed at baseline, 3, 6, and 12 months with planned extended follow-up, and the primary outcome is restoration survival over 12 months. Secondary outcomes include technical complications (fracture, chipping, screw loosening), peri-implant biological measures, marginal bone level changes on radiographs, and patient-reported satisfaction.

Why it matters

Potential benefit: If successful, this could offer a faster and potentially lower-cost alternative to zirconia with comparable short-term survival and patient satisfaction for implant restorations.

How similar studies have gone: Laboratory data and short-term clinical reports on 3D-printed resins show promising mechanical and esthetic results, but high-quality randomized clinical evidence for definitive 3D-printed implant restorations remains limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants must meet all of the following:
* Age ≥18 years.
* Have one or two osseointegrated dental implants requiring prosthetic restoration.
* Demonstrate stable peri-implant tissues with no signs of inflammation or implant mobility.
* Maintain good oral hygiene and controlled periodontal status.
* Require either:
* A single implant-supported crown, or
* A short-span (maximum 3-unit) implant-supported fixed partial denture (FPD) supported by two implants in the mandibular anterior region.

Exclusion Criteria:

* Participants are excluded if they have any of the following:
* Severe parafunctional habits (e.g., bruxism).
* Uncontrolled systemic diseases affecting bone metabolism or healing.
* Peri-implantitis or compromised implant stability.
* Requirement for cantilever prostheses or long-span restorations, or FPDs in areas other than the mandibular anterior region.

Where it's running

  • Mohammed Elsawy
    Shibīn al Kawm, Egypt
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.