3D printed customized prosthetic legs for amputees

LIMBER UniLeg: Rapid, On-demand, and Scaled-up Manufacturing of Customized Transtibial Prosthetic Legs for Amputees

Not applicable Interventional LIMBER Prosthetics & Orthotics Inc · NCT06648798

This study is testing a new 3D printed prosthetic leg for amputees to see if it works as well as traditional ones while being cheaper and faster to make.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years to 75 Years
SexAll
SponsorLIMBER Prosthetics & Orthotics Inc Industry-sponsored
Locations2 sites (La Jolla, California and 1 other locations)
Trial IDNCT06648798 on ClinicalTrials.gov

What this trial studies

The LIMBER UniLeg is a clinical trial evaluating a 3D printed single-piece transtibial prosthetic limb designed to be equivalent to traditional passive prosthetic limbs while significantly reducing manufacturing costs and time. This single-site study involves 30 participants who will use their existing prosthetic device for one month and the LIMBER UniLeg for another month, assessing its effectiveness and safety. The trial aims to address the global prosthetic accessibility crisis by leveraging digital technologies to create affordable and accessible solutions for amputees.

Who should consider this trial

Good fit: Ideal candidates are unilateral transtibial amputees aged 18 to 75 who have been amputated for over a year and currently use a passive prosthetic device.

Not a fit: Patients who are diabetic or have significant health issues that could affect their participation may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a more affordable and accessible prosthetic option for amputees, improving their quality of life.

How similar studies have performed: While other studies have explored 3D printed prosthetic sockets, this approach of a fully 3D printed unibody prosthesis is novel and has not been widely tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Provision of signed and dated informed consent form.
2. Stated willingness to comply with all study procedures and availability for the duration of the study.
3. Persons, aged 18 to 75
4. In good general health as determined by clinical site monitor
5. Weight \< 125kg
6. Are not diabetic (self reported)
7. Be a unilateral transtibial amputee of more than 1 year since amputation
8. Have an existing prosthetic device(s) that does not use sensors or motors (is passive)
9. Live in the Southern California region (within 50 miles of UCSD)
10. Has sufficient sensation in residual limb as tested by the clinical site monitor
11. Agreement to adhere to Lifestyle Considerations throughout study duration 11a. Use the testing device (EPD or UniLeg) only during the testing periods. 11b. Walk at least 14,000 steps per week (average of 1 mile per day). 11c. Maintain a similar diet and activity level throughout study duration (no abrupt changes of weight, activity, etc.)

Exclusion Criteria:

1. Not currently using a prosthetic device
2. Prosthetic device with active motors, sensors, etc.
3. Pregnancy (due to fall risk)
4. Diabetic (due to poor limb sensation), self reported
5. No under 18 (due to inability to consent)
6. No over 75 (due to fall risk)
7. Poor proprioception or sensation at the residual limb

Where this trial is running

La Jolla, California and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Amputation of Lower LimbProsthesisNon-inferiority Trial of ProthesisTrans-tibial amputationLimber Unileg3D Printed
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.