3D photo measurement of facial symmetry after lower or middle face reconstruction

Development, Validation and Clinical Application of a Method for Quantitative 3D Assessment of Facial Symmetry After Facial Reconstruction Using Three-dimensional Stereophotogrammetry

Using 3D stereophotogrammetry and questionnaires, this project will see if facial symmetry measurements relate to aesthetic outcomes in adults after reconstruction of the lower or middle face.

Quick facts

• Study type: Observational
• Enrollment: 50 (estimated)
• Ages: 18 Years and up
• Sex: All
• Sponsor: Assistance Publique Hopitaux De Marseille (Academic / other)
• Locations: 1 site (Marseille)
• Trial ID: NCT06534970 on ClinicalTrials.gov

What this trial studies

This observational project enrolls adults who underwent reconstruction of the lower or middle third of the face with pedicled or free flaps after tumor resection, osteonecrosis, or traumatic loss. Participants receive three-dimensional stereophotogrammetry imaging and complete questionnaires about aesthetic outcome and quality of life during routine follow-up at the PROMOD cluster in Marseille. The goal is to identify which objective symmetry measures correlate with patient-reported aesthetic results and life impact. Findings aim to inform more personalized surgical planning and early correction of poor aesthetic outcomes.

Who should consider this trial

Good fit: Adults (18+) who had reconstruction of the lower or middle third of the face with pedicled or microanastomosed free flaps after tumor, osteonecrosis, or trauma and who had surgery and routine follow-up in the three PROMOD departments at Marseille CHU Conception are ideal candidates.

Not a fit: Patients who had prior different reconstructions of the same facial region, those who cannot read French, minors, people under legal guardianship, or those who did not receive care at the specified Marseille departments are unlikely to benefit from participating.

Why it matters

Potential benefit: If successful, the work could help surgeons predict and prevent poor aesthetic outcomes, improving appearance and quality of life for future patients.

How similar studies have performed: Three-dimensional stereophotogrammetry is an established and reliable technique for measuring facial surface symmetry, but using those measurements to predict patient-reported aesthetic outcomes after complex reconstruction remains relatively novel.

Eligibility criteria

Inclusion Criteria:

* Male or female, 18 years of age or older,
* Patient having given non-opposition for participation in this study,
* Reconstruction of the lower or middle third of the face by pedicled flap or microanastomosed free flap following excision of a benign or malignant tumor of the oral cavity or face, osteonecrosis of the jaws, loss of facial traumatic substance,
* Surgery and routine follow-up performed in the 3 departments (maxillofacial surgery, ENT, plastic and reconstructive surgery) of the PROMOD cluster at Marseille's CHU Conception

Exclusion Criteria:

* History of reconstruction of the lower or middle third of the face other than that being evaluated at one year for this study,
* Subjects covered by articles L1121-5 to 1121-8 of the French Public Health Code (minors, adults under guardianship, patients deprived of their liberty, pregnant or breast-feeding women),
* Persons who cannot read and understand the French language well enough to be able to give their non-opposition to participating in the research.

Where this trial is running

Marseille

• Assistance Publique - Hôpitaux de Marseille — Marseille, France (Recruiting)

Study contacts

• Study coordinator: Nicolas GRAILLON, MD

Conditions Facial Reconstruction; Three-dimensional stereophotogrammetry; Facial symmetry