3D isometric movement training for stroke recovery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of 3D isometric movement training on both healthy individuals and stroke survivors with impaired movement. Participants will engage in a virtual reality reaching task using a robotic arm, where they will receive visual feedback through a virtual avatar. The study aims to compare the accuracy of movements under unconstrained and constrained conditions to understand how sensory alterations affect performance in a three-dimensional environment. By analyzing the differences in movement errors, researchers hope to gain insights into improving rehabilitation techniques for stroke patients.

Why it matters

Who can join: the full rules

Inclusion criteria, neurotypical participants

* 18 years old

No history of stroke

Ability to provide informed consent .

Exclusion criteria, neurotypical participants

Severe medical problems (including cardiovascular, orthopedic, or neurological)

Medical problems affecting movement, range of motion, strength, or coordination of the upper extremities.

Visual deficits that would influence the ability to perform the experiment . This will be assessed using the following assessments:

1. Visual field deficits will be assessed using the BIVABA acuity testing. (cutoff score \> 20/100)
2. Depth perception deficits will be assessed using the Stereofly test (require at least an angle of stereopsis at 16 inches is 3,552 seconds of arc).

   4\) Blood pressure above 140 systolic and/or 90 diastolic mmHG

   5\) Blood oxygen reading of less than 92% by finger pulse oximeter testing.

   Inclusion Criteria , Stroke participants
   * 18 years old

   Chronic stroke (8+ months post)

   Available medical records and radiographic information about lesion locations

   Hemiparesis

   Primary motor cortex involvement

   Some degree of both shoulder and elbow movement capability

   Exclusion Criteria , Stroke participants

   Bilateral paresis

   Aphasia, cognitive impairment, or affective dysfunction that would influence the ability to perform the experiment, This will be assessed using the Mini Mental State Examination31, with cut-off scores (adjusted for education level) as follows:

   Participants whose education are 7th grade or lower, a score 22 or lower

   Participants whose education attainment level is 8th grade or some high school (but not a graduate), a score of 24 or lower

   Participants whose education attainment level is high school graduate, a score of 25 or lower

   Participants whose education attainment level is some college or higher, a score 26 or lower

   Visual deficits, and hemispatial neglect that would prevent the participants from seeing the targets. A vision test will be done if the participant indicates in their screen that their stroke has affected their vision. This will be tested using the following assessments:

   Visual field loss will be assessed using the BIVABA acuity test10. (cutoff score \> 20/100)

   Visual Extinction and Inattention using Star Cancellation Test9. (cutoff score of \<44)

   Depth perception deficits will be assessed using the Stereofly test (require at least an angle of stereopsis at 16 inches is 3,552 seconds of arc).

   Modified Ashworth score of 4 at shoulder or elbow joints.

   Rated below 15 on the FMUE scale

   Inability to provide an informed consent

   severe current medical problems

   Severe sensory deficit in the affected limb (Cannot be absent in any part of affected UE)

   diffuse/multiple lesion sites or multiple stroke events

   Inability to attain and maintain testing positions

   Botox or other botulinum toxin injection to the affected upper extremity within the previous 4 months

   Concurrent participation in upper extremity rehabilitation either as part of a research intervention protocol or a prescribed therapy

   Neurological, neuromuscular, or orthopedic diseases (i.e. injuries to your affected arm or hand)

   Other neurological issues (Parkinson's, CP)

   Blood Pressure above 140 systolic and/or 90 diastolic mmHg

   Blood oxygen reading of less than 92% on finger pulse oximetry testing.

Where it's running

• Shirley Ryan AbilityLab
  Chicago, Illinois, United States Recruiting

Study contacts

• Principal investigator: James L Patton, PhD — Shirley Ryan AbilityLab
• Study coordinator: Arturo Ramirez
• Email: aramire4@uic.edu
• Phone: 312-238-1379

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals

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• Web-based therapy using action observation and mirror therapy for arm weakness after stroke

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• Remote Ischaemic Conditioning for Fatigue After Stroke 2

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• Dual-task balance training plus computer-based cognitive training after stroke

  In adults who recently had a stroke, the study tests whether adding computerized cognitive exercises to balance training improves balance and other recovery outcomes.

  Recruiting Matia Foundation · San Sebastián, GUIPUZCOA · NCT07913620

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.