3D changes in the upper airway after surgery for sleep apnea

3D Volumetric Changes in the Upper Airway After Maxillomandibular Advancement in Obstructive Sleep Apnea Syndrome Patients and the Implication on Quality of Life: A Prospective Registry

Observational AZ Sint-Jan AV · NCT02762175

This study is looking at how surgery for sleep apnea changes the shape of the upper airway in patients to see how it affects their breathing and quality of life.

Quick facts

Study typeObservational
Enrollment150 (estimated)
SexAll
SponsorAZ Sint-Jan AV Academic / other
Locations1 site (Bruges)
Trial IDNCT02762175 on ClinicalTrials.gov

What this trial studies

This observational study aims to create a prospective database that tracks 3D volumetric changes in the upper airway of patients diagnosed with obstructive sleep apnea (OSAS) who undergo maxillomandibular advancement (MMA) surgery. The study will collect data on the apnea-hypopnea index (AHI) and quality of life (QOL) from patients treated by Dr. Neyt since January 2015. By analyzing these changes, the researchers hope to better understand the implications of MMA surgery on patient outcomes and airway anatomy.

Who should consider this trial

Good fit: Ideal candidates for this study are patients of all ages and genders diagnosed with obstructive sleep apnea, specifically those with an apnea-hypopnea index of 5 or greater.

Not a fit: Patients with morbid obesity or those deemed non-eligible by the treating surgeon will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide valuable insights into the effectiveness of MMA surgery in improving airway structure and patient quality of life.

How similar studies have performed: While there have been studies on MMA surgery for OSAS, this specific approach focusing on 3D volumetric changes and quality of life is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients of all ages
* Patients of all genders
* Patients diagnosed with OSAS, based on an AHI ≥ 5
* All consecutive OSAS patients operated by N. Neyt from January 2015 onwards

Exclusion Criteria:

* Patients not eligible according to abovementioned criteria
* Patients with morbid obesity (BMI \>35), if judged non-eligible by the treating surgeon

Where this trial is running

Bruges

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Obstructive Sleep Apneamaxillomandibular advancementobstructive sleep apneaapnea-hypopnea indexquality of life
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.