3D analysis of bone loss in patients with complete dentures
3D Quantification Assessment of Mandibular Bone Resorption Using STL Registration-Based Superimposition Following Removable Complete Denture Occlusal Equilibration
This study is testing how wearing complete dentures affects bone loss in the jaw by comparing 3D scans of patients' jaws before and after they start using the dentures.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 6 (estimated) |
| Ages | 45 Years to 75 Years |
| Sex | All |
| Sponsor | Badr University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Cairo) |
| Trial ID | NCT06562972 on ClinicalTrials.gov |
What this trial studies
This study utilizes STL registration-based superimposition to assess mandibular bone resorption in patients using removable complete dentures. By aligning and comparing digital models of the mandible before and after denture use, the study aims to provide precise measurements of bone changes. The process involves advanced 3D scanning and quantification techniques, focusing on the impact of occlusal equilibration on bone resorption patterns. The research seeks to enhance understanding of how masticatory forces affect bone health in edentulous patients.
Who should consider this trial
Good fit: Ideal candidates are completely edentulous individuals aged 45 to 75 with a Class I skeletal relationship and adequate inter-arch space.
Not a fit: Patients with temporomandibular disorders, uncontrolled diabetes, or severe psychiatric disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved denture designs and treatment protocols that minimize bone loss in patients.
How similar studies have performed: Previous studies using similar 3D analysis techniques have shown promising results in understanding bone resorption patterns.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria * Completely edentulous patients ranging from age 45 to 75 years * Angle's Class I skeletal relationship * Normal facial symmetry * Cooperative patients * Adequate inter-arch space not less than 12mm Exclusion Criteria * Temporomandibular disorders * Uncontrolled diabetes * Bleeding disorders or anticoagulant therapy * Flabby tissues or sharp mandibular residual ridge. * Heavy smokers. * Patient's with neuromuscular disorders * Patients on chemotherapy or radiotherapy * Severe psychiatric disorders * Angle's class II and III skeletal relationship
Where this trial is running
Cairo
- Badr university in Cairo — Cairo, Egypt (Recruiting)
Study contacts
- Principal investigator: Shady Elnaggar — Badr university in Cairo
- Study coordinator: Shady Elnaggar
- Email: shady.mahmoud@buc.edu.eg
- Phone: +201122110085
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.