3-D printed versus conventional overdentures for people with ectodermal dysplasia
Official title: Adaptation and Patient Satisfaction of 3-D Printed Versus Conventional Acrylic Overdentures in Patients With Ectodermal Dysplasia: A Crossover Prospective Clinical Trial
Run by Cairo University · NCT07468019 · Data updated 2026-11-12
This project will test whether 3-D printed overdentures provide better fit, comfort, and satisfaction than conventional acrylic overdentures for people aged 10–35 with ectodermal dysplasia who have some remaining upper teeth.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 10 Years to 35 Years |
| Sex | All |
| Enrollment | 11 (estimated) |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Cairo) |
| Status | Recruiting |
| Started | February 1, 2026 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | March 12, 2026 |
| Trial ID | NCT07468019 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are people aged 10–35 with ectodermal dysplasia who have a few remaining teeth in the upper jaw and can attend all follow-up visits.
✕Probably not a fit
Patients with large anatomical limitations requiring surgery, allergy to denture resins, active pathological changes of the residual ridges, or inability to cooperate with follow-up visits are unlikely to benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Participants aged 10–35 with ectodermal dysplasia and a few remaining maxillary teeth will receive either a 3-D printed overdenture or a conventionally processed acrylic overdenture and will be followed over time for denture adaptation and patient-reported outcomes. Clinical measures of fit and retention and standardized questionnaires of satisfaction will be collected at scheduled follow-up visits. The comparison focuses on whether digital 3-D printing reduces polymerization shrinkage and improves adaptation versus conventional processing. Oral health and any complications will be monitored throughout the follow-up period.
Why it matters
Potential benefit: If successful, 3-D printed overdentures could produce better-fitting, more comfortable dentures with higher patient satisfaction and fewer adjustment visits.
How similar studies have gone: Clinical evidence specifically in ectodermal dysplasia is scarce, but early reports of digitally manufactured and 3-D printed dentures in other populations have shown promising improvements in adaptation and workflow.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age must range from 10-35 years. * Must have a few remaining teeth in the maxilla. * Must will to attend all follow-ups. Exclusion Criteria: * Extreme anatomical limitations such as a large torus that requires surgical excision. * Allergy to dentures made of resins. * Pathological changes of residual ridges as recurrent or persistent ulcers, osteomyelitis and infections. 4\. Patients with medical or psychological conditions as physical disability or mental retardation that hinder cooperation in the follow up visits and answering the questionnaires.
Where it's running
-
Faculty of Dentistry, Cairo University
Cairo, Egypt Recruiting
Study contacts
- Study coordinator: Yasmine Hisham Mohsen
- Email: yasmine.hisham@dentistry.cu.edu.eg
- Phone: +201007771412
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.