3-D printed versus conventional overdentures for people with ectodermal dysplasia
Adaptation and Patient Satisfaction of 3-D Printed Versus Conventional Acrylic Overdentures in Patients With Ectodermal Dysplasia: A Crossover Prospective Clinical Trial
NA · Cairo University · NCT07468019
This project will test whether 3-D printed overdentures provide better fit, comfort, and satisfaction than conventional acrylic overdentures for people aged 10–35 with ectodermal dysplasia who have some remaining upper teeth.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 11 (estimated) |
| Ages | 10 Years to 35 Years |
| Sex | All |
| Sponsor | Cairo University (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT07468019 on ClinicalTrials.gov |
What this trial studies
Participants aged 10–35 with ectodermal dysplasia and a few remaining maxillary teeth will receive either a 3-D printed overdenture or a conventionally processed acrylic overdenture and will be followed over time for denture adaptation and patient-reported outcomes. Clinical measures of fit and retention and standardized questionnaires of satisfaction will be collected at scheduled follow-up visits. The comparison focuses on whether digital 3-D printing reduces polymerization shrinkage and improves adaptation versus conventional processing. Oral health and any complications will be monitored throughout the follow-up period.
Who should consider this trial
Good fit: Ideal candidates are people aged 10–35 with ectodermal dysplasia who have a few remaining teeth in the upper jaw and can attend all follow-up visits.
Not a fit: Patients with large anatomical limitations requiring surgery, allergy to denture resins, active pathological changes of the residual ridges, or inability to cooperate with follow-up visits are unlikely to benefit from this intervention.
Why it matters
Potential benefit: If successful, 3-D printed overdentures could produce better-fitting, more comfortable dentures with higher patient satisfaction and fewer adjustment visits.
How similar studies have performed: Clinical evidence specifically in ectodermal dysplasia is scarce, but early reports of digitally manufactured and 3-D printed dentures in other populations have shown promising improvements in adaptation and workflow.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age must range from 10-35 years. * Must have a few remaining teeth in the maxilla. * Must will to attend all follow-ups. Exclusion Criteria: * Extreme anatomical limitations such as a large torus that requires surgical excision. * Allergy to dentures made of resins. * Pathological changes of residual ridges as recurrent or persistent ulcers, osteomyelitis and infections. 4\. Patients with medical or psychological conditions as physical disability or mental retardation that hinder cooperation in the follow up visits and answering the questionnaires.
Where this trial is running
Cairo
- Faculty of Dentistry, Cairo University — Cairo, Egypt (RECRUITING)
Study contacts
- Study coordinator: Yasmine Hisham Mohsen
- Email: yasmine.hisham@dentistry.cu.edu.eg
- Phone: +201007771412
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Ectodermal Dysplasia