12-week physical activity program for women with early-stage hormone receptor–positive breast cancer
Official title: Effects of Physical Activity in Early Stage Hormone Receptor Positive Breast Cancer Patients
Run by Centro di Riferimento Oncologico - Aviano · NCT07539038 · Data updated 2026-11-12
This project will try whether a 12-week physical activity program improves quality of life for women with early-stage hormone receptor–positive breast cancer who are on adjuvant endocrine therapy.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 44 (estimated) |
| Sponsor | Centro di Riferimento Oncologico - Aviano Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Aviano, Pordenone) |
| Status | Recruiting |
| Started | April 3, 2025 |
| Main results expected | December 31, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | April 20, 2026 |
| Trial ID | NCT07539038 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 18 or older with early-stage (I–IIIa) hormone receptor–positive breast cancer who are on adjuvant endocrine therapy, can provide informed consent, and can participate in the ANDOS 12-week physical activity program are ideal candidates.
✕Probably not a fit
Patients with metastatic disease, hormone receptor–negative tumors, those currently receiving chemotherapy, those with uncontrolled cardiovascular disease, a history of vertebral or femoral fractures, or those unable to attend the ANDOS program are unlikely to benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective observational study enrolls women with early-stage (I–IIIa) hormone receptor–positive breast cancer receiving adjuvant endocrine therapy who agree to join a 12-week physical activity program run by ANDOS onlus. Participants receive baseline and follow-up assessments of quality of life and related health measures while participating in the organized exercise program. The study does not randomize interventions but records outcomes associated with real-world program participation. Collected data will be analyzed to describe changes in quality of life and other physical health indicators over the 12-week period.
Why it matters
Potential benefit: If successful, the program could show that a structured 12-week exercise program improves quality of life and physical health for early-stage hormone receptor–positive breast cancer survivors.
How similar studies have gone: Previous randomized and observational studies in breast cancer survivors have shown that exercise programs can improve quality of life and physical functioning, so this approach builds on established evidence.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with early stage (I-IIIa) hormone receptor-positive breast cancer receiving adjuvant endocrine therapy * Female patients ≥18 years of age * Written informed consent must be obtained before any study-related assessment is performed * Participation to the Medicina and Sport physical activity program organized by Andos Pordenone Exclusion Criteria: * Patients with early hormone receptor negative breast cancer * Patients with early hormone receptor positive breast cancer receiving chemotherapy * Patients with advanced/metastatic breast cancer. * Patients receiving active treatment for secondary primary tumors (excluding basal cell carcinoma or in situ neoplasias). * Patients with history of vertebral and/or femoral fractures * Patients with CVDs not optimally controlled by medical therapy
Where it's running
-
Centro di Riferimento Oncologico di Aviano
Aviano, Pordenone, Italy Recruiting
Study contacts
- Study coordinator: Mattia Garutti
- Email: mattia.garutti@cro.it
- Phone: 0434659092
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.