Study summary
A new once-daily pill added about an hour of good movement a day
1.7 vs 0.6extra hours a day of good movement, tavapadon vs placebo
What was tested
Tavapadon, a pill that activates two dopamine receptors (D1 and D5), added to levodopa in people whose medication wears off between doses.
What they found
- People gained 1.7 hours a day of "on" time without troublesome involuntary movements, against 0.6 hours with placebo.
- "Off" time fell by 1.9 hours a day, against 0.9 with placebo.
- Side effects were reported by 71.7% on tavapadon and 55.1% on placebo.
- The label warns about low blood pressure on standing, hallucinations and impulse-control problems.
What it means
A new first-in-class option that can be used with or without levodopa. It treats symptoms; it does not slow the disease.
Last reviewed 2026-11-14 by the Find a Trial editorial team.
Information on this page is for educational purposes and is not medical advice.
Always consult qualified healthcare professionals about clinical trial participation.