Study summary
A new non-opioid painkiller did no better than placebo for sciatica
2.02 vs 1.98points of pain relief on a 0 to 10 scale, suzetrigine vs placebo
What was tested
Suzetrigine, approved for short-term pain after surgery or injury, tested for 12 weeks in pain from a pinched nerve in the lower back.
What they found
- Pain fell by 2.02 points with suzetrigine and 1.98 with placebo.
- The result was released by the company and has not been published in full.
- The drug is approved for short-term pain, not long-term back pain.
What it means
The first new class of painkiller in decades has not yet shown it helps long-term back or nerve pain.
Last reviewed 2026-11-14 by the Find a Trial editorial team.
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