Study summary
Surgery to remove lymph nodes cured most men with early-spread seminoma, without chemotherapy
98%kept normal ejaculation after surgery
What was tested
A pooled look at studies of lymph node surgery (RPLND) as the first treatment for stage II seminoma, in place of chemotherapy or radiation. None compared directly with standard care.
What they found
- About 14% had the cancer return over a median of 38 months.
- Serious complications occurred in about 4%.
- 98% kept normal ejaculation, a key concern with this surgery.
What it means
A way to avoid chemotherapy and its long-term effects for some men, decided case by case at experienced centers.
Last reviewed 2026-11-14 by the Find a Trial editorial team.
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