Study summary
A drug-coated balloon kept most short strictures open for five years
58%had lasting symptom relief at 5 years without more treatment
What was tested
Optilume, a balloon coated with paclitaxel that widens the urethra and releases a drug to slow scar regrowth, in men with short, recurring strictures of the bulbar urethra. No comparison group.
What they found
- At 5 years, 58% had their urinary symptoms at least halved without further treatment.
- About 72% avoided another procedure.
- Erections were not affected.
- Many men left the study before 5 years, which adds uncertainty.
What it means
A reasonable choice for some men with short strictures who want to avoid open surgery. Urethroplasty still has higher long-term success.
Last reviewed 2026-11-14 by the Find a Trial editorial team.
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