Study summary

Radiation after complete surgery halved the risk of an atypical meningioma coming back

ROAM/EORTC-1308 trial · 157 people, phase 3 · Presented September 2026 (EANO); published in The Lancet

14%recurred within about 5 years with radiation, vs 30% with scans alone

What was tested

Radiotherapy soon after complete removal of an atypical (grade 2) meningioma, against regular MRI scans and treatment only if the tumor returned.

What they found

Recurrence over about 5 years was 14% with radiation vs 30% with scans alone.
Quality of life, memory and thinking showed no clear differences between groups so far.
Most side effects were mild.

What it means

Settles a long-standing debate: radiation after complete surgery is now likely to become standard for atypical meningioma.

EORTC ↗ ← Back to the outlook

Last reviewed 2026-11-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.