Study summary

Risankizumab tripled remission at induction and kept most responders in remission for a year

Risankizumab trials · Two phase 3 trials · Published September 2024, JAMA; FDA approved 2024

20.3%in remission at 12 weeks, vs 6.2% with placebo

What was tested

Risankizumab, another IL-23 blocker, against placebo, for induction and then maintenance of ulcerative colitis.

What they found

What it means

A second IL-23 option, already approved for Crohn's disease.

JAMA, via PubMed ↗ ← Back to the outlook
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.