Study summary
A lower radiation dose cleared early anal cancer just as often, with fewer side effects
92% vs 87%had all visible cancer gone at 6 months, lower vs standard dose
What was tested
A lower dose of radiation (41.4 Gy) against the standard dose (50.4 Gy), both with chemotherapy, for small anal cancers that had not spread.
What they found
- At 6 months, 92% on the lower dose and 87% on the standard dose had no visible cancer.
- Severe short-term side effects occurred in 35% vs 46%.
- The main result, how often the cancer comes back by 3 years, is still to be reported.
What it means
Supports gentler treatment for early anal cancer. Final 3-year results will decide whether it becomes standard.
Last reviewed 2026-11-14 by the Find a Trial editorial team.
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