Study summary

Placebo injections alone straightened curves by about 5 degrees

Placebo injection review · 382 men in placebo groups of 7 trials · Published August 2026, Journal of Sexual Medicine

5.1degrees of curve improvement with placebo injections alone

What was tested

A pooled look at the placebo groups of trials testing injections into Peyronie's plaques.

What they found

Men given placebo injections improved by about 5 degrees on average.
This was not linked to age or number of injections.

What it means

Any new injection treatment has to beat this. Uncontrolled reports of small improvements should be read with caution.

J Sex Med, via PubMed ↗ ← Back to the outlook

Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.