Study summary
An immune-modulating pill failed to improve movement symptoms
What was tested
Laquinimod, an oral immunomodulator, against placebo for Huntington disease.
What they found
- Did not improve the primary measure of motor symptoms.
- Some brain-volume measures differed, but without clinical benefit.
What it means
One of several setbacks that pushed the field toward lowering huntingtin directly.
Last reviewed 2026-11-15 by the Find a Trial editorial team.
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