Study summary

A steroid injection at the back of the head is being tested as a bridge treatment

Occipital nerve injection trial · Randomized, placebo-controlled · Published September 2025, Cephalalgia

What was tested

Greater occipital nerve injection with methylprednisolone against placebo as transitional therapy while verapamil takes effect in episodic cluster headache.

What they found

• Verapamil doses needed did not differ between groups.

What it means

Occipital nerve injections remain widely used as a bridge, though this trial did not show a verapamil-sparing effect.