Study summary

A bispecific antibody cleared visible disease in about 3 in 4 people with relapsed mantle cell lymphoma

Glofitamab phase 1/2 study · 60 people, phase 1/2 · Published October 2024, Journal of Clinical Oncology

78.3%complete response rate

What was tested

Glofitamab, a bispecific antibody that links T cells to lymphoma cells, given for a fixed period, for relapsed or refractory mantle cell lymphoma, most after a BTK inhibitor.

What they found

What it means

Led to the GLOBRYTE phase 3 trial against standard choices after BTK inhibitors.

J Clin Oncol, via PubMed ↗ ← Back to the outlook
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