Study summary

A once-daily pill cut attacks by 83%

CHAPTER-3 trial (deucrictibant XR) · Phase 3 · Topline results 2026; presented November 2026 (ACAAI)

83%fewer monthly attacks than with placebo

What was tested

Deucrictibant extended-release, an oral bradykinin B2 receptor blocker taken daily, against placebo, to prevent attacks.

What they found

What it means

Could become an oral alternative to injected prevention; a soft-capsule form is tested for attacks.

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Last reviewed 2026-11-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.