Study summary

Cadonilimab plus chemotherapy shrank most tumors as first treatment

Cadonilimab phase 2 · Phase 2 in China · Reported November 2025

81%of tumors shrank

What was tested

Cadonilimab, one antibody that blocks both PD-1 and CTLA-4, with paclitaxel and cisplatin as first treatment for advanced disease. No comparison group.

What they found

What it means

High response rates are common in small first-treatment trials. A randomized trial around surgery is now running.

Targeted Oncology ↗ Trial record NCT05522894 ↗ ← Back to the outlook
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.