Study summary

Starving tumors of arginine added 1.6 months of life

ATOMIC-Meso trial · 249 people, phase 2-3, double-blind · Published April 2024, JAMA Oncology

+1.6 momedian survival gain: 9.3 vs 7.7 months

What was tested

Pegargiminase, an enzyme that removes arginine from the blood, with chemotherapy, against placebo with chemotherapy, in non-epithelioid pleural mesothelioma, the harder-to-treat types.

What they found

What it means

A modest gain in the subtypes with the fewest options.

JAMA Oncol, via PubMed ↗ ← Back to the outlook
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