Study summary

Adding atezolizumab to chemotherapy shrank more than half of advanced thymic carcinomas

MARBLE trial · 48 people · Published March 2025, Lancet Oncology

56%had their tumors shrink

What was tested

Atezolizumab, an immunotherapy, with carboplatin and paclitaxel as first treatment for advanced or recurrent thymic carcinoma, in Japan. No comparison group.

What they found

What it means

Promising, but needs a comparison against chemotherapy alone. Thymic carcinoma carries a higher risk of immune side effects than other cancers.

Lancet Oncol, via PubMed ↗ ← Back to the outlook
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