Study summary

After two earlier pills failed, asciminib worked three times as often as bosutinib

ASCEMBL trial, 4-year results · Phase 3 · Published August 2025, Blood Advances

33.8%major molecular response at 3 years, vs 10.5% with bosutinib

What was tested

Asciminib against bosutinib for chronic-phase CML in people who had already tried at least two other tyrosine kinase inhibitor pills.

What they found

What it means

Confirmed asciminib as the treatment of choice after two earlier pills.

Blood Adv, via PubMed ↗ ← Back to the outlook
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