Study summary

New US guidelines bring the newer drugs into standard care

2026 AGA/AASLD guideline · Clinical guideline · Published October 2026

What was tested

Updated joint guideline from the American Gastroenterological Association and American Association for the Study of Liver Diseases on treating PBC.

What they found

Recommends second-line options for people who do not respond to ursodiol.
Suggests linerixibat as an option for moderate to severe itch.

What it means

Turns the 2024-2026 approvals into routine practice.

Guideline Central ↗ ← Back to the outlook

Last reviewed 2026-11-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.