Sponsor or institution

Clinical trials and research at Xencor, Inc.

• 7Clinical trials
• 24Countries

Newest trials

All recruiting trials (7)

• XmAb412 in healthy adults

  This Phase 1 study tests XmAb412 in healthy adults to see how it behaves in the body and how safe it is.

  Recruiting at 2 sites Phase 1 Xencor, Inc. · Joondalup, Western Australia and 1 other locations · NCT07713485

• Safe and tolerable dose test of XmAb541 plus XmAb808 in advanced ovarian cancer

  This study tests whether the drug combination XmAb541 and XmAb808 is safe and tolerable in adults with advanced ovarian cancer and looks at initial tumor responses.

  Recruiting at 4 sites Phase 1 Xencor, Inc. · Lake Success, New York and 3 other locations · NCT07593092

• Phase 1 safety test of XmAb657 in healthy adults and people with myositis, scleroderma, or Sjögren's

  This study will test whether subcutaneous injections of XmAb657 are safe and well tolerated in healthy adults and people with autoimmune diseases such as idiopathic inflammatory myopathies, systemic sclerosis, or primary Sjögren's syndrome.

  Recruiting Phase 1 Xencor, Inc. · Melbourne · NCT07284797

• Plamotamab injections for adults with moderate to severe rheumatoid arthritis.

  This trial will try subcutaneous plamotamab injections to see if they are safe and tolerated in adults with moderate to severe rheumatoid arthritis.

  Recruiting at 3 sites Phase 1 Xencor, Inc. · Tbilisi and 2 other locations · NCT07230353

• Evaluating XmAb942 in Healthy Individuals and Those with Ulcerative Colitis

  This study is testing a new drug called XmAb942 in healthy people and those with ulcerative colitis to see how safe it is and how well it works.

  Recruiting at 112 sites Phase 1/2 Xencor, Inc. · Scottsdale, Arizona and 113 other locations · NCT06619990

• Safety and tolerability of XmAb541 in patients with advanced solid tumors

  This study is testing a new drug called XmAb541 to see if it's safe and how well it works for people with advanced solid tumors like ovarian and endometrial cancer.

  Recruiting at 27 sites Phase 1 Xencor, Inc. · Duarte, California and 26 other locations · NCT06276491

• Treatment of advanced clear cell kidney cancer with XmAb®819

  This study is testing a new drug called XmAb®819 to see if it’s safe and effective for people with advanced clear cell kidney cancer who haven't responded to other treatments.

  Recruiting at 26 sites Phase 1 Xencor, Inc. · Phoenix, Arizona and 25 other locations · NCT05433142

Quick answers

How many clinical trials run by Xencor, Inc. are recruiting right now?

7, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 24 countries. The most sites are in United States (4 trials), Australia (3 trials), Spain (3 trials), Georgia (2 trials), Moldova (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 6, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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